Serum HMGB1 level is correlated with serum I-FABP level in neonatal patients with necrotizing enterocolitis

BMC Pediatrics

Table 2 Pearson’s analysis for the correlation among HMGB1, I-FABP and inflammatory factors in neonatal NEC patients and suspected stage I NEC patients

		HMGB1	I-FABP	CRP	IL-1β	IL-6	TNF-α
HMGB1	Pearson correlation	1	0.511	0.001	0.282	0.292	0.026
HMGB1	P	-	< 0.001	0.986	< 0.001	< 0.001	0.708
I-FABP	Pearson correlation	0.511	1	0.056	0.426	0.340	0.092
I-FABP	P	< 0.001	-	0.425	< 0.001	< 0.001	0.189
CRP	Pearson correlation	0.001	0.056	1	0.109	-0.005	0.034
CRP	P	0.986	0.425	-	0.119	0.946	0.624
IL-1β	Pearson correlation	0.282	0.426	0.109	1	0.383	-0.069
IL-1β	P	< 0.001	< 0.001	0.119	-	< 0.001	0.324
IL-6	Pearson correlation	0.292	0.340	-0.005	0.383	1	-0.043
IL-6	P	< 0.001	< 0.001	0.946	< 0.001	-	0.541
TNF-α	Pearson correlation	0.026	0.092	0.034	-0.069	-0.043	1
TNF-α	P	0.708	0.189	0.624	0.324	0.541	-

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