Skip to main content

Table 4 Association between conditional variables and neurodevelopmental delay at 12 months old in boys

From: Physical growth and neurodevelopment during the first year of life: a cohort study of the Japan Environment and Children’s Study

[Model 1] Conditional variables at birth, 4, 7 and 10 months old

Total

Communication

Gross motor

Fine motor

Problem solving

Personal-Social

 

1,441/8,488 (17.0 %)

396/8,534 (4.6 %)

458/8,532 (5.4 %)

372/8,526 (4.4 %)

511/8,519 (6.0 %)

303/8,506 (3.6 %)

Length at birth

1.00 (0.94–1.07)

0.99 (0.87–1.12)

1.01 (0.90–1.13)

1.03 (0.90–1.17)

0.97 (0.87–1.09)

1.00 (0.86–1.16)

Weight at birth

0.97 (0.91–1.03)

0.97 (0.85–1.10)

0.96 (0.86–1.08)

1.00 (0.88–1.14)

0.97 (0.87–1.08)

0.92 (0.79–1.06)

cLength at 4 months old

0.92 (0.87–0.98)

0.87 (0.78–0.98)

0.98 (0.89–1.09)

0.81 (0.73–0.91)

0.86 (0.78–0.95)

0.79 (0.70–0.90)

crWeight at 4 months old

0.90 (0.84–0.97)

0.96 (0.83–1.10)

0.88 (0.77-1.00)

0.89 (0.78–1.03)

0.86 (0.76–0.97)

0.84 (0.72–0.98)

cLength at 7 months old

1.07 (1.00-1.14)

1.14 (0.99–1.30)

1.13 (0.99–1.28)

1.08 (0.94–1.24)

1.05 (0.95–1.18)

1.01 (0.89–1.18)

crWeight at 7 months old

0.98 (0.89–1.07)

0.81 (0.65-1.00)

0.91 (0.74–1.10)

0.90 (0.72–1.10)

1.00 (0.85–1.15)

1.03 (0.86–1.22)

cLength at 10 months olda

0.98 (0.90–1.07)

0.91 (0.77–1.08)

1.13 (0.95–1.33)

1.00 (0.83–1.20)

1.10 (0.94–1.27)

0.87 (0.73–1.05)

crWeight at 10 months oldb

0.94 (0.87–1.03)

0.94 (0.83–1.16)

0.90 (0.81–1.05)

1.02 (0.85–1.33)

0.96 (0.84–1.17)

0.97 (0.81–1.26)

[Model 2] Conditional variables at birth, 4 and 7 months old

Total

Communication

Gross motor

Fine motor

Problem solving

Personal-Social

2,281/13,689 (16.7 %)

612/13,757 (4.4 %)

698/13,759 (5.1 %)

614/13,753 (4.5 %)

814/13,742 (5.9 %)

481/13,722 (3.5 %)

Length at birth

1.02 (0.97–1.07)

1.00 (0.90–1.10)

1.03 (0.94–1.14)

1.01 (0.91–1.12)

1.00 (0.91–1.09)

1.04 (0.93–1.18)

Weight at birth

0.96 (0.91–1.01)

0.96 (0.87–1.07)

0.94 (0.85–1.03)

0.97 (0.87–1.07)

0.94 (0.86–1.03)

0.90 (0.80–1.01)

cLength at 4 months old

0.93 (0.89–0.97)

0.88 (0.80–0.97)

0.97 (0.89–1.06)

0.85 (0.78–0.93)

0.89 (0.82–0.97)

0.81 (0.73–0.90)

crWeight at 4 months old

0.90 (0.85–0.95)

0.88 (0.79–0.99)

0.89 (0.80–0.99)

0.91 (0.81–1.01)

0.85 (0.77–0.93)

0.90 (0.79–1.01)

cLength at 7 months old

1.08 (1.02–1.14)

1.09 (0.97–1.23)

1.14 (1.02–1.27)

1.16 (1.03–1.29)

1.11 (1.00-1.23)

1.05 (0.95–1.19)

crWeight at 7 months old

1.00 (0.92–1.08)

0.87 (0.72–1.04)

0.99 (0.84–1.15)

0.94 (0.79–1.10)

0.99 (0.86–1.11)

1.15 (0.99–1.31)

[Model 3] Conditional variables at birth, 4 and 10 months old

Total

Communication

Gross motor

Fine motor

Problem solving

Personal-Social

3,478/21,577 (16.1 %)

910/21,687 (4.2 %)

1086/21,684 (5.0 %)

923/21,677 (4.3 %)

1,232/21,656 (5.7 %)

723/21,626 (3.3 %)

Length at birth

1.00 (0.96–1.04)

0.93 (0.85–1.01)

0.98 (0.91–1.06)

0.99 (0.91–1.08)

1.02 (0.95–1.10)

0.97 (0.88–1.07)

Weight at birth

0.97 (0.93–1.01)

0.98 (0.90–1.06)

0.98 (0.91–1.06)

0.99 (0.91–1.08)

0.93 (0.87-1.00)

0.92 (0.83–1.01)

cLength at 4 months old

0.92 (0.89–0.95)

0.85 (0.79–0.92)

0.97 (0.90–1.04)

0.85 (0.79–0.91)

0.87 (0.82–0.93)

0.83 (0.76–0.90)

crWeight at 4 months old

0.92 (0.88–0.96)

0.94 (0.85–1.03)

0.91 (0.84-1.00)

0.89 (0.82–0.98)

0.86 (0.80–0.93)

0.87 (0.79–0.96)

cLength at 10 months olda

1.00 (0.96–1.05)

0.91 (0.85–0.99)

1.00 (0.92–1.09)

1.00 (0.91–1.09)

1.05 (0.97–1.14)

1.01 (0.92–1.11)

crWeight at 10 months oldb

1.02 (0.97–1.07)

1.01 (0.92–1.11)

0.91 (0.85–0.99)

0.96 (0.88–1.06)

1.01 (0.93–1.10)

1.08 (0.98–1.17)

  1. Data represent the adjusted relative risk (95 % confidence interval). All of the conditional variables and the following covariates were included together in the model: maternal age and smoking, maternal and paternal education, family income, and home speech stimulation. a,bThe values of the variables were different between the models because these variables were estimated from different combinations of the previous data ([model 1] at birth, 4 and 7 months old; [model 3] at birth and 4 months old).
  2. cLength conditional length; crWeight conditional relative weight