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Table 3 Logistic Regression Models, Association of Antibiotic Pretreatment and Duration on Culture Positivity

From: Impact of antibiotic pretreatment on cultures in children with osteomyelitis and septic arthritis: a retrospective review

Predictor

Culture

Comparison (reference = no pretreatment)

Odds Ratio for Positive Culture

Pretreatment (vs. none) with antibiotics

  

ORa (95% CIb)

P-value

N = 525

Blood

0.90 (0.56–1.44)

0.66

N = 90

Bone

0.77 (0.25–2.34)

0.64

N = 262

Joint

0.71 (0.39–1.28)

0.26

N = 196

Other

1.18 (0.58–2.41)

0.65

Hours of antibiotics (for pretreated cultures)

Culture

Comparison

(reference = 0- < 4 h)

OR (95% CI)

P-value

N = 113

Blood

4 to < 24 h

1.24 (0.44–3.52)

0.90

  

>  24 h

1.34 (0.35–5.22)

0.78

N = 50

Bone

4 to < 24 h

1.11 (0.06–19.93)

0.90

  

>  24 h

1.57 (0.08–31.4)

0.68

N = 91

Joint

4 to < 24 h

1.36 (0.36–5.06)

0.93

  

>  24 h

1.67 (0.35–8.01)

0.58

N = 139

Other

4 to < 24 h

0.77 (0.24–2.46)

0.28

  

>  24 h

1.60 (0.44–5.77)

0.25

  1. Note: All logistic regression models adjusted for age, gender, race, duration of symptoms at presentation, and C-reactive protein
  2. aOR: Odds Ratio
  3. bCI: Confidence Interval