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Table 1 Demographics of the BA and control patients enrolled in this study

From: Programmed cell death protein-1 (PD-1) protects liver damage by suppressing IFN-γ expression in T cells in infants and neonatal mice

Variables BA (n = 68) CC (≤4 months, n = 9) CC (> 4 months, n = 17) NHS (n = 7)
Age at surgery, mean (SD), days 70.62 ± 21.5 100 ± 25.98 1134 ± 553.3 58.29 ± 14.16
Sex, M/F 26/42 3/6 4/13 6/1
ALT, mean (SD), U/L 206.1 ± 143.7 66.11 ± 68.78*** 58.38 ± 77.74**** 211.2 ± 108.6n.s
AST, mean (SD), U/L 292.6 ± 183.3 88.67 ± 95.78**** 59.00 ± 61.68**** 223.4 ± 114.0n.s
GGT, mean (SD), U/L 658.5 ± 541.3 188.3 ± 294.5*** 150.7 ± 241.5**** 293.2 ± 331.3*
DBIL, mean (SD), μmol/L 175.2 ± 278.8 28.26 ± 50.41**** 20.45 ± 28.67**** 127 ± 35.17n.s
TBIL, mean (SD), μmol/L 163 ± 43.29 40.09 ± 69.41**** 24.27 ± 34.19**** 162.5 ± 54.19n.s
  1. BA biliary atresia, CC choledochal cyst, NHS neonatal hepatis syndrome, SD standard deviation. Significance was determined by Mann-Whitney U test. n.s: not significant. ****p < 0.0001,***p < 0.001,**p < 0.01, *p < 0.05.