Skip to main content

Table 3 Association between NIRS measurements and ECHO-Doppler markers of Aortic flow

From: End-organ saturations correlate with aortic blood flow estimates by echocardiography in the extremely premature newborn – an observational cohort study

  Rsat at ECHO Mean 58.6% (12.6) rFTOE at ECHO Mean 37.7% (13.3) Csat at ECHO Mean 65.8% (8.6) cFTOE at ECHO Mean 30.1% (8.7)
Pre-ductal aorta – Ascending Aorta (Suprasternal View)
 VTI Mean: 0.11 (0.03) meter ICC: < 0.10
β(95%CI): −23(− 214–168)
p-value: 0.81
30 observations
ICC: < 0.10
β(95%ΧΙ): 60(− 144–265)
p-value: 0.56
30 observations
ICC: 0.75
β(95%CI): 39(−70–148)
p-value: 0.48
36 observations
ICC: 0.48
β(95%CI): −40(− 107–114)
p-value: 0.95
36 observations
 Output Mean: 492 (136) or 500a (149) mL/kg/min ICC: < 0.10
β(95%CI): − 0.01(− 0.05–0.02)
p-value: 0.47
30 observations
ICC: < 0.10
β(95%CI): 0.02(− 0.02–0.06)
p-value: 0.29
30 observations
ICC: 0.75
β(95%CI): − 0.02(− 0.04 – − 0.002)
p-value: 0.03
36 observations
ICC: 0.47
β(95%CI): 0.02(.01–0.04)
p-value: 0.006
36 observations
 Peak systolic velocity of the ascending Aorta (suprasternal view) Mean: 0.91 (0.21) or 0.93 (0.21)a ICC: < 0.10
β(95%CI): −8(− 33–17)
p-value: 0.54
30 observations
ICC: < 0.10
β(95%CI): 13(− 14–40)
p-value: 0.33
30 observations
ICC: 0.66
β(95%CI): − 6(− 20–8)
p-value: 0.39
36 observations
ICC: 0.48
β(95%CI): 12(− 2–26)
p-value: 0.09
36 observations
Post-ductal aorta - Descending Aorta (subcostal view)
 VTI Mean: 0.04 (0.02) meter ICC: 0.12
β(95%CI): 4(−137–144)
p-value: 0.96
56 observations
ICC: 0.95
β(95%CI): − 27(− 177–123)
p-value: 0.72
55 observations
ICC: 0.61
β(95%CI): 46(− 33–124)
p-value: 0.25
69 observations
ICC: 0.50
β(95%CI): −47(− 132–38)
p-value: 0.28
68 observations
 Output Mean: 126 (56) or 122a (53) mL/kg/min ICC: 0.11
β(95%CI): 0.01(−0.05–0.07)
p-value: 0.85
56 observations
ICC: 0.02
β(95%CI): − 0.02(− 0.08–0.05)
p-value: 0.63
55 observations
ICC: 0.59
β(95%CI): 0.01(− 0.03–0.04)
p-value: 0.64
69 observations
ICC: 0.57
β(95%CI): 0.01(− 0.03–0.04)
p-value: 0.74
68 observations
 Peak systolic velocity Mean: 0.52 (0.20) or 0.51a (0.19) m/s ICC: 0.11
β(95%CI): −1(− 18–15)
p-value: 0.87
56 observations
ICC: 0.04
β(95%CI): 0.1 (− 18–19)
p-value: 0.99
55 observations
ICC: 0.60
β(95%CI): 3(− 5–12)
p-value: 0.44
69 observations
ICC: 0.53
β(95%CI): − 1(− 11–9)
p-value: 0.84
68 observations
Post-ductal aorta - Descending Aorta (suprasternal view)
 VTI Mean 0.11 (0.05) meter ICC: 0.83
β(95%CI): 180(108–252)
p-value: < 0.001
21 observations
ICC: 0.71
β(95%CI): − 188(− 264 – − 111)
p-value: < 0.001
20 observations
ICC: 0.37
β(95%CI): 71(7–135)
p-value: 0.03
25 observations
ICC < 0.10
β(95%CI): − 94(− 161 – − 28)
p-value: 0.005
24 observations
 Output Mean: 279 (122) or 273a (124) mL/kg/min ICC: 0.23
β(95%CI): 0.03(−0.01–0.08)
p-value: 0.16
21 observations
ICC: 0.03
β(95%CI): − 0.05(− 0.10 – − 0.01)
p-value: 0.03
20 observations
ICC: 0.96
β(95%CI): 0.018 (0.002–0.034)
p-value: 0.02
25 observations
ICC: 0.98
β(95%CI): − 0.03(− 0.04 – − 0.01)
p-value: < 0.001
24 observations
 Peak systolic velocity Mean: 0.94 (0.32) or 0.97a (0.33) m/s ICC: 0.47
β(95%CI): 23(7–38)
p-value: 0.004
21 observations
ICC: 0.38
β(95%CI): − 37(− 50 – − 23)
p-value: < 0.001
20 observations
ICC: 0.92
β(95%CI): 7(−2–16)
p-value: 0.129
25 observations
ICC: 0.88
β(95%CI): − 8(− 19–3)
p-value: 0.17
24 observations
  1. Linear mixed effect models with random intercepts (for continuous variables). Mean expressed with (standard deviation). Statistically significant correlations are in bold type. Outputs in mL/kg/min. Peak velocities in meter/second
  2. Ao aorta, β β coefficient, Csat cerebral saturation, ECHO echocardiography, FTOE fractional tissue oxygen extraction, ICC intraclass correlation, Rsat renal saturation, VTI velocity time integral in meters
  3. aECHO parameters mean (SD) for corresponding renal NIRS measures or cerebral NIRS measures