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Table 2 Associations of epidemiologic factors with eczema

From: Interaction between antibiotic use and MS4A2 gene polymorphism on childhood eczema: a prospective birth cohort study

Phenotypes

Eczema

n (%)

Non-eczema

n (%)

P value a

OR (95% CI) b

Gender

 Boy

95 (56.9)

212 (49.4)

 

1

 Girl

72 (43.1)

217 (50.6)

0.20

0.78 (0.53, 1.14)

Gestational age (wk)

 < 37

3 (1.8)

18 (4.2)

 

1

 37–39

126 (75.0)

293 (68.3)

0.44

1.84 (0.39, 8.61)

 ≥ 40

39 (23.2)

118 (27.5)

0.64

1.47 (0.30, 7.15)

Birth weight (g)

 < 2500

2 (1.2)

14 (3.3)

 

1

 2500–4000

152 (90.5)

377 (87.9)

0.44

2.07 (0.32, 13.24)

 ≥ 4000

14 (8.3)

38 (8.9)

0.48

2.04 (0.28, 14.68)

Delivery mode

 Vaginal

44 (26.2)

105 (24.5)

 

1

 Cesarean section

124 (73.8)

324 (75.5)

0.31

0.80 (0.51, 1.23)

Parity

 None

158 (94.0)

390 (90.9)

 

1

 ≥ 1

10 (6.0)

39 (9.1)

0.16

0.57 (0.26, 1.25)

Antibiotic use

 No

72 (42.9)

255 (60.0)

 

1

 Yes

96 (57.1)

170 (40.0)

0.00

2.02 (1.37, 2.98)

Home pet sitting c

 No

133 (79.2)

355 (83.5)

 

1

 Yes

35 (20.8)

70 (16.5)

0.51

1.18 (0.72, 1.92)

In-home secondhand smoke exposure

 No

66 (39.3)

213 (50.2)

 

1

 Yes

102 (60.7)

211 (49.8)

0.16

1.32 (0.89, 1.96)

Home decoration

 No

152 (91.0)

394 (92.7)

 

1

 Yes

15 (9.0)

31 (7.3)

0.43

1.31 (0.67, 2.57)

Parental atopy d

 No

120 (72.3)

346 (81.6)

 

1

 Yes

46 (27.7)

78 (18.4)

0.06

1.53 (0.98, 2.39)

Maternal education

 Middle school or lower

3 (1.8)

15 (3.5)

 

1

 High school

14 (8.3)

57 (13.3)

0.87

1.13 (0.24, 5.40)

 College or higher

151 (89.9)

356 (83.2)

0.43

1.81 (0.42, 7.85)

Paternal education

 Middle school or lower

2 (1.2)

6 (1.4)

 

1

 High school

17 (10.2)

51 (12.0)

0.65

0.64 (0.09, 4.45)

 College or higher

148 (88.6)

367 (86.6)

0.44

0.48 (0.07, 3.11)

Family income (CNY)

 < 100 K

44 (26.3)

129 (30.2)

 

1

 ≥ 100 K

101 (60.5)

226 (52.9)

0.24

1.32 (0.84, 2.08)

 Unknown

22 (13.2)

72 (16.9)

0.77

0.91 (0.49, 1.70)

  1. OR odds ratio, CI confidence interval
  2. a P Values were tested by multivariate logistic regression
  3. b All parameter estimates were adjusted for other covariates
  4. c keeping cats or dogs at home
  5. d Parental atopy was referred to those parents who had asthma, allergic rhinitis or atopic dermatitis along with detectable specific IgE