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Table 2 Comparison of VA levels and core symptoms in ASD children with and without sleep disturbances

From: RETRACTED ARTICLE: Vitamin A deficiency and sleep disturbances related to autism symptoms in children with autism spectrum disorder: a cross-sectional study

Variable

Without sleep disturbancesa (n = 174)

With sleep disturbancesa (n = 682)

P value

VA levelsb

 VA levels, mean (SD)

1.04 (0.15)

0.60(0.27)

< 0.001***

 VAN, % (n)

29.89 (52/174)

16.86 (115/682)

< 0.001***

 MVAD, % (n)

70.11 (122/174)

22.29 (152/682)

 VAD, % (n)

0 (0/174)

60.85 (415/682)

CARS score, % (n)

 Mild to moderate degree (30–36)

54.60 (95/174)

5.43 (37/682)

< 0.001***

 Severe degree (37–60)

45.40 (79/174)

94.57 (645/682)

ABC total score, mean (SD)

64.13 (7.77)

99.57 (25.05)

< 0.001***

SRS total score, mean (SD)

91.55 (15.58)

141.24 (30.06)

< 0.001***

  1. Abbreviations: ASD Autism spectrum disorder, VA Vitamin A, SD Standard deviation, CARS Childhood Autism Rating Scale, ABC Autism Behavior Checklist, SRS Social Responsiveness Scale, CSHQ Childhood Sleep Habit Questionnaire
  2. ***P < 0.001
  3. aThe individuals with total CSHQ scores below 41 were classified as without sleep disturbances; those with over 41 were classified as with sleep disturbances [22]
  4. bSerum retinol concentrations ≥1.05 μmol/L were defined as Vitamin A Normal (VAN); < 1.05 μmol/L and ≥ 0.7 μmol/L were defined as Marginal Vitamin A Deficiency (MVAD); < 0.7 μmol/L were defined as Vitamin A Deficiency (VAD) [29]