Table 3 Association between post-extubation mode and other parameters
From: Reintubation rates after extubation to different non-invasive ventilation modes in preterm infants
Parameters | NCPAP N = 97 | NIPPV N = 77 | NC N = 26 | P-Value |
|---|---|---|---|---|
Birth Weight (gm) | 1686.7 ± 500.8 | 1408.5 ± 494.9 | 2101.9 ± 505.5 | < 0.0001 |
(mean ± SD) | 1555 (1342.5, | 1320 (1020, | 2140 (1631.3, |  |
Median (IQR) | 2011.3) | 1685) | 2412.5) | Â |
Birth Weight (gm) | ||||
  > 1000 g | 93 (95.9) | 60 (77.9) | 26 (100) | < 0.0001 |
  ≤ 1000 g | 4 (4.1) | 17 (22.1) | 0 (0) |  |
Gestational Age (weeks) | 31.2 ± 2.4 | 30 ± 2.3 | 33.6 ± 2.1 | < 0.0001 |
Median (IQR) | 31 (29, 33) | 29 (28, 31) | 34 (32, 36) | Â |
Apgar Score at 1 min | 6.7 ± 2.3 | 6.7 ± 1.9 | 6.4 ± 3.1 | 0.891 |
Median (IQR) | 7 (5, 9) | 7 (5, 8) | 8 (4.5, 9) | Â |
Apgar Score at 5 min | 8.6 ± 1.6 | 8.5 ± 1.1 | 8.4 ± 1.9 | 0.934 |
Median (IQR) | 9 (8, 10) | 9 (8, 9) | 9 (7.5, 10) | Â |
Duration of Mechanical Ventilation (days) | 2.4 ± 2.3 | 3.4 ± 4.1 | 2.7 ± 2.8 | 0.105 |
Median (IQR) | 1 (1, 3) | 2 (1, 4) | 2 (1, 3.3) | Â |
Duration of Non-Invasive Ventilation (days) | 3.7 ± 5.3 | 3.6 ± 4.2 | 2.7 ± 2.4 |  |
Median (IQR) | 2 (1, 4) | 2 (1, 4) | 2 (1, 3.8) | 0.786 |
Days till reintubation | 1.9 ± 1.85 | 2.7 ± 1.9 | – | 0.446 |
Median (IQR) | 1 (1, 2) | 2 (1, 4) | Â | Â |
Age at Extubation (day) | 2.52 ± 2.55 | 3.41 ± 3.91 | 3.56 ± 2.62 | 0.115 |
Median (IQR) | 1 (1, 4) | 2 (1, 4.3) | 4 (1, 4.5) | Â |
Maternal GBS Status | ||||
 Negative | 89 (91.8) | 67 (88.2) | 25 (96.2) | 0.331 |
 Positive | 6 (6.2) | 9 (11.8) | 1 (3.8) |  |
 Unknown | 2 (2.1) | 0 (0) | 0 (0) |  |
Maternal Antenatal Steroids | ||||
 No | 46 (47.9) | 35 (45.5) | 16 (61.5) | 0.356 |
 Yes | 50 (52.1) | 42 (54.5) | 10 (38.5) |  |
Need for PPV during resuscitation | ||||
 No | 44 (45.8) | 22 (28.9) | 13 (50) | 0.042 |
 Yes | 52 (54.2) | 54 (71.1) | 13 (50) |  |
Need for resuscitation medication. | ||||
 No | 95 (97.9) | 77 (100) | 25 (96.2) | 0.309 |
 Yes | 2 (2.1) | 0 (0) | 1 (3.8) |  |
Surfactant Administration | ||||
 No | 21 (21.6) | 9 (11.7) | 20 (76.9) | < 0.0001 |
 Yes | 76 (78.4) | 68 (88.3) | 6 (23.1) |  |
Number of Surfactant Doses | ||||
 1 | 57 (75) | 35 (52.2) | 6 (85.7) | 0.022 |
 2 | 18 (23.7) | 26 (38.8) | 1 (14.3) |  |
 3 | 1 (1.3) | 6 (9) | 0 (0) |  |
Need for intubation during resuscitation. | ||||
 No | 52 (53.6) | 40 (51.9) | 14 (53.8) | 0.972 |
 Yes | 45 (46.4) | 37 (48.1) | 12 (46.2) |  |
Mode of Delivery | ||||
 Vaginal delivery | 19 (19.8) | 8 (10.4) | 7 (26.9) | 0.095 |
 Caesarian Section | 77 (80.2) | 69 (89.6) | 19 (73.1) |  |
Pre-extubation Ventilation Mode | ||||
 PC-AC + VG | 90 (96.8) | 73 (96.1) | 24 (96) | 0.416 |
 SIMV | 3 (3.2) | 1 (1.3) | 1 (4) |  |
 HFOV | 0 (0) | 2 (2.6) | 0 (0) |  |
Patent Ductus Arteriosus (PDA) | ||||
 No | 81 (83.5) | 54 (70.1) | 23 (88.5) | 0.044 |
 Yes | 16 (16.5) | 23 (29.9) | 3 (11.5) |  |
HsPDA* | ||||
 No | 11 (64.7) | 3 (13.0) | 2 (66.7) | 0.009 |
 Yes | 6 (35.3) | 20 (87.0) | 1 (33.3) |  |
Reintubation | ||||
 No | 87 (88.8) | 71 (91.0) | 26 (100) | 0.203 |
 Yes | 11(11.2) | 6 (9.0) | 0 (0) |  |
Necrotizing Enterocolitis (NEC) | ||||
 No | 92 (94.8) | 69 (89.6) | 25 (96.2) | 0.322 |
 Yes | 5 (5.2) | 8 (10.4) | 1 (3.8) |  |
Intestinal Perforation | ||||
 No | 96 (99) | 74 (96.1) | 26 (100) | 0.300 |
 Yes | 1 (1) | 3 (3.9) | 0 (0) |  |
Air Leak | ||||
 No | 88 (90.7) | 72 (93.5) | 19 (73.1) | 0.011 |
 Yes | 9 (9.3) | 5 (6.5) | 7 (26.9) |  |
BPD | ||||
 No | 93 (95.9) | 65 (84.4) | 26 (100) | 0.006 |
 Yes | 4 (4.1) | 12 (15.6) | 0 (0) |  |
BPD Grade | ||||
 Mild | 2 (50) | 9 (75) |  | 0.350 |
 Moderate | 2 (50) | 3 (25) |  |  |
Sepsis status | ||||
 No | 94 (96.9) | 74 (96.1) | 26 (100) | 0.922 |
 Yes | 3 (3.1) | 3 (3.9) | 0 (0) |  |