Skip to main content

Table 2 Adjusted incidence rate ratios, ED visits, inpatient hospitalizations, and physician encounters, for children identified as hemoglobinopathy carriers through NBS and screen negative matched population controls

From: Health services use by children identified as heterozygous hemoglobinopathy mutation carriers via newborn screening

  ED Visits Inpatient hospitalizations Physician encounters
<  1 year of age ≥1 year of age <  1 year of age ≥1 year of age <  1 year of age ≥1 year of age
NBS result
 Carrier 1.11 (1.06–1.17) 1.03 (0.98–1.07) 0.97 (0.89–1.06) 1.14 (1.03–1.25) 1.02 (1.00–1.04) 0.92 (0.90–0.94)
 Control REF REF REF REF REF REF
Sex
 Male 1.18 (1.14–1.23) 1.20 (1.16–1.23) 1.34 (1.26–1.44) 1.28 (1.19–1.39) 1.09 (1.08–1.11) 1.10 (1.08–1.12)
 Female REF REF REF REF REF REF
Gestational age
  < 37 weeks 1.33 (1.23–1.45) 1.21 (1.13–1.30) 2.54 (2.27–2.82) 1.36 (1.17–1.57) 1.59 (1.54–1.63) 1.06 (1.02–1.09)
  ≥ 37 weeks REF REF REF REF REF REF
Birth weight
  < 2500 g 1.05 (0.96–1.15) 1.07 (0.99–1.15) 2.03 (1.81–2.28) 1.68 (1.44–1.96) 1.72 (1.67–1.77) 1.15 (1.11–1.20)
  ≥ 2500 g REF REF REF REF REF REF
Socioeconomic status
  ‘Lower’ 1.17 (1.12–1.21) 1.07 (1.04–1.10) 1.05 (0.99–1.13) 1.05 (0.97–1.14) 1.00 (0.99–1.01) 0.97 (0.96–0.99)
 ‘Higher’ REF REF REF REF REF REF