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Table 2 ORs of mildly and markedly increased ALTa for age and degree of obesity, stratified by sex

From: Prevalence of increased transaminases and its association with sex, age, and metabolic parameters in children and adolescents with obesity – a nationwide cross-sectional cohort study

 

OR (99% CI, P value)

OR (99% CI, P value)

Mildly increased ALT, n = 4461

Markedly increased ALT, n = 1245

Males

Females

Males

Females

Age (years)

1.15 (1.13–1.18, < 0.001)

0.97 (0.95–0.99, 0.002)

1.34 (1.29–1.38, < 0.001)

1.06 (1.02–1.10, < 0.001)

Degree of obesity

 Class I obesity

Ref

Ref

Ref

Ref

 Class II obesity

1.52 (1.29–1.80, < 0.001)

1.57 (1.33–1.86 < < 0.001)

2.03 (1.60–2.58, < 0.001)

1.59 (1.15–2.20, < 0.001)

 Class III obesity

2.27 (1.82–2.82), < 0.001)

2.17 (1.75–2.70, < 0.001)

3.73 (2.77–5.02, < 0.001)

3.57 (2.52–5.06, < 0.001)

  1. Abbreviations: ALT alanine aminotransferase, OR odds ratio, CI confidence interval, Ref reference group
  2. a Compared to normal ALT group
  3. ORs were adjusted for age and degree of obesity
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BMC Pediatrics

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