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Table 2 Demographics

From: The role of early-onset-sepsis in the neurodevelopment of very low birth weight infants

 

No-EOS

EOS

p

N = 166

135

31

 

Male, a)

54 (40)

15 (48)

0.514

Gestational Age Weeks (wk + d), b)

29 + 2 (± 2 + 2)

27 + 6 (± 2 + 0)

0.001

Birth weight g, b)

1160.56 (± 267.62)

974.97 (± 276.40)

0.001

Umbilical artery pH, b)

7.30 (± 0.09)

7.29 (± 0.08)

0.811

Apgar 1′/5′/10′, c)

7 / 8 / 8

7 / 8 / 8

0.125 / 0.041 / 0.057

Apgar 1′/5′/10′ c)

(1; 6–8; 9 / 3; 7–8; 9 / 5; 8–9 10)

(4; 6–8; 8 / 3; 7–8; 9 / 3; 8–8; 9)

 

CRIB-Score, c)

1 (0 / 0–3 / 11)

3 (0 / 1.75–5.25 / 12)

0.001

Highest Bilirubin, μmol/l, b)

143.85 (± 23.44)

148.74 (± 62.31)

0.472

Antenatal steroids 1 dose / 2 doses, a)

72 (53) / 35 (26)

18 (58) / 11 (35)

0.633 / 0.284

Ceaseraen delivery, a)

121 (90)

30 (97)

0.366

Patent ductus arteriosus, d)

36 (27)

10 (32)

0.830

BPD, f)

6 (4)

6 (19)

0.011

Retinopathia neonatorum ≥3, d)

2 (1)

0

0.999

Intraventricular haemorrhage ≥3, d)

4 (3)

2 (6)

0.312

Periventricular leukomalacia, d)

1 (1)

1 (3)

0.340

Parental Education Score 1/2 d); 3/4 a); a)

1 (1) / 7 (5) / 76 (56) / 47 (35)

0 / 2 (6) / 17 (55) / 10 (32)

0.999 / 0.667 / 0.999 / 0.999

Max CrP 72 h postnatal, c)

0.62 (0 / 0–1.525 / 8.37)

14.36 (5.37 / 9.5–28.07 / 68.45)

0.000

Leukocytes in first CBC, ×109, b)

9.9 (±5.71)

10.22 (±11.09)

0.824

Leukopenia a)

9 (7)

10 (32)

0.000

Leukocytosis d)

4 (3)

3 (10)

0.122

Combinded abnormal WBC a)

13 (10)

13 (42)

0.000

Thrombocytes in first CBC, ×  109, b)

181.8 (±69.7)

173.4 (±71.7)

0.547

Thrombocytopenia, a)

40 (30

14 (45)

0.146

Severe thrombocytopenia, d)

3 (2)

2 (6)

0.234

Last Maternal CrP prior to Birth,c)

7.21 (0 / 2.49–20.41 / 70.77)

8.8 (0 / 2.04–29.16 / 64.93)

0.541

PROM < 24 h / >  24 h />  1 week, d)

36 (27) / 10 (7) / 17 (13)

3 (10) / 0 / 12 (39)

0.059 / 0.211 / 0.001

Chorioamnionitis, d)

8 (6)

6 (19)

0.026

LOS d)

27 (20)

9 (29)

0.211

Age at BSIDII, month, e)

24 (23–30)

25 (24–31)

0.323

Total sepsis symptoms c) b

3 (0 / 2–3.5 / 6)

4 (2 / 3–5 / 7)

0.000

  1. a) n (%), χ2-test; b) mean, SD, 1-Way ANOVA; c) median, min, IQR, max; Kruskal-Wallis-Test; d) n (%), Fisher’s exact test; e) median, min – max, Mann-Whitney-U-Test
  2. adisplayed are n of individual parental Education score categories as defined in the methods section
  3. bdisplayed is the median total of clinical symptoms associated with EOS as defined in the methods section
  4. Abbreviations: BPD Bronchopulmonary dysplasia, BSID Bayley Scales of Infant Development II, CBC Complete blood count, CRIB Clinical risk index for babies, EOS Early onset sepsis, LOS Late onset sepsis, PROM Premature rupture of membranes, WBC White blood cell count