From: The role of early-onset-sepsis in the neurodevelopment of very low birth weight infants
No-EOS | EOS | p | |
---|---|---|---|
N = 166 | 135 | 31 | |
Male, a) | 54 (40) | 15 (48) | 0.514 |
Gestational Age Weeks (wk + d), b) | 29 + 2 (± 2 + 2) | 27 + 6 (± 2 + 0) | 0.001 |
Birth weight g, b) | 1160.56 (± 267.62) | 974.97 (± 276.40) | 0.001 |
Umbilical artery pH, b) | 7.30 (± 0.09) | 7.29 (± 0.08) | 0.811 |
Apgar 1′/5′/10′, c) | 7 / 8 / 8 | 7 / 8 / 8 | 0.125 / 0.041 / 0.057 |
Apgar 1′/5′/10′ c) | (1; 6–8; 9 / 3; 7–8; 9 / 5; 8–9 10) | (4; 6–8; 8 / 3; 7–8; 9 / 3; 8–8; 9) | |
CRIB-Score, c) | 1 (0 / 0–3 / 11) | 3 (0 / 1.75–5.25 / 12) | 0.001 |
Highest Bilirubin, μmol/l, b) | 143.85 (± 23.44) | 148.74 (± 62.31) | 0.472 |
Antenatal steroids 1 dose / 2 doses, a) | 72 (53) / 35 (26) | 18 (58) / 11 (35) | 0.633 / 0.284 |
Ceaseraen delivery, a) | 121 (90) | 30 (97) | 0.366 |
Patent ductus arteriosus, d) | 36 (27) | 10 (32) | 0.830 |
BPD, f) | 6 (4) | 6 (19) | 0.011 |
Retinopathia neonatorum ≥3, d) | 2 (1) | 0 | 0.999 |
Intraventricular haemorrhage ≥3, d) | 4 (3) | 2 (6) | 0.312 |
Periventricular leukomalacia, d) | 1 (1) | 1 (3) | 0.340 |
Parental Education Score 1/2 d); 3/4 a); a) | 1 (1) / 7 (5) / 76 (56) / 47 (35) | 0 / 2 (6) / 17 (55) / 10 (32) | 0.999 / 0.667 / 0.999 / 0.999 |
Max CrP 72 h postnatal, c) | 0.62 (0 / 0–1.525 / 8.37) | 14.36 (5.37 / 9.5–28.07 / 68.45) | 0.000 |
Leukocytes in first CBC, ×109, b) | 9.9 (±5.71) | 10.22 (±11.09) | 0.824 |
Leukopenia a) | 9 (7) | 10 (32) | 0.000 |
Leukocytosis d) | 4 (3) | 3 (10) | 0.122 |
Combinded abnormal WBC a) | 13 (10) | 13 (42) | 0.000 |
Thrombocytes in first CBC, × 109, b) | 181.8 (±69.7) | 173.4 (±71.7) | 0.547 |
Thrombocytopenia, a) | 40 (30 | 14 (45) | 0.146 |
Severe thrombocytopenia, d) | 3 (2) | 2 (6) | 0.234 |
Last Maternal CrP prior to Birth,c) | 7.21 (0 / 2.49–20.41 / 70.77) | 8.8 (0 / 2.04–29.16 / 64.93) | 0.541 |
PROM < 24 h / > 24 h /> 1 week, d) | 36 (27) / 10 (7) / 17 (13) | 3 (10) / 0 / 12 (39) | 0.059 / 0.211 / 0.001 |
Chorioamnionitis, d) | 8 (6) | 6 (19) | 0.026 |
LOS d) | 27 (20) | 9 (29) | 0.211 |
Age at BSIDII, month, e) | 24 (23–30) | 25 (24–31) | 0.323 |
Total sepsis symptoms c) b | 3 (0 / 2–3.5 / 6) | 4 (2 / 3–5 / 7) | 0.000 |