From: The role of early-onset-sepsis in the neurodevelopment of very low birth weight infants
no Follow-Up | Follow-Up | p | |
---|---|---|---|
N = 342 a) | 176 (51) | 166 (49) | |
EOS a) | 23 (13) | 31 (19) | 0.155 |
Male, a) | 81 (46) | 69 (42) | 0.406 |
Gestational Age Weeks (wk + d), b) | 29 + 4 (± 2 + 3) | 29 + 1 (± 2 + 2) | 0.085 |
Birth weight g, b) | 1146 (± 282) | 1126 (± 278) | 0.507 |
Umbilical artery pH, b) | 7.33 (± 0.30) | 7.29 (± 0.09) | 0.124 |
Apgar 1′/5′/10′, c) | 7 / 8 / 8 | 7 / 8 / 8 | 0.250 / 0.144 / 0.022 |
Apgar 1′/5′/10′ c) | (0; 6–8; 9 / 4; 7–8; 9 / 6; 8–8; 10) | (1; 6–8; 9 / 3; 7–8; 9 / 5; 8–8; 10) | |
CRIB-Score, c) | 1 (0 / 1–2 / 10) | 1 (0 / 1–4 / 12) | 0.548 |
Highest Bilirubin, μmol/l, b) | 145.80 (± 28.88) | 144.77 (± 33.99) | 0.762 |
Antenatal steroids 1 dose / 2 doses, a) | 87 (49) / 53 (30) | 90 (54) / 46 (28) | 0.478 / 0.624 |
Ceaseraen delivery, a) | 162 (92) | 151 (91) | 0.589 |
Patent ductus arteriosus, a) | 35 (20) | 46 (28) | 0.408 |
BPD, d) | 15 (9) | 12 (7) | 0.693 |
Retinopathia neonatorum ≥3, d) | 0 | 2 (1) | 0.235 |
Intraventricular haemorrhage ≥3, d) | 1 (1) | 6 (4) | 0.061 |
Periventricular leukomalacia, d) | 0 | 2 (1) | 0.235 |
Parental Education Score 1/2 d); 3/4 a) a | 2 (1) / 10 (6) / 96 (55) / 49 (28) | 1 (1) / 9 (5) / 93 (56) / 57 (34) | 0.620 / 0.817 / 0.584 / 0.405 |
Max CrP 72 h postnatal, c) | 1.04 (0 / 0–3.91 / 52.37) | 1.04 (0 / 0–5.08 / 68.45) | 0.748 |
Leukocytes in first CBC, ×109,b) | 9.50 (± 5.86) | 9.96 (± 7.04) | 0.512 |
Last Maternal CrP prior to Birth, c) | 6.82 (0 / 1.65–17.25 / 118.3) | 7.43 (0 / 2.42–21.98 / 70.77) | 0.330 |
PROM < 24 h a) / > 24 h e) /> 1 week, a) | 55 (31) / 15 (9) / 29 (16) | 39 (23) / 10 (6) / 29 (17) | 0.108 / 0.412 / 0.699 |
Chorioamnionitis, a) | 21 (12) | 14 (8) | 0.374 |
LOS a) | 20 (11) | 36 (22) | 0.427 |
Total sepsis symptoms c) b | 3 (0 / 1–4 / 7) | 3 (0 / 1–4 / 7) | 0.127 |