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Table 1 Demographics

From: The role of early-onset-sepsis in the neurodevelopment of very low birth weight infants

 

no Follow-Up

Follow-Up

p

N = 342 a)

176 (51)

166 (49)

 

EOS a)

23 (13)

31 (19)

0.155

Male, a)

81 (46)

69 (42)

0.406

Gestational Age Weeks (wk + d), b)

29 + 4 (± 2 + 3)

29 + 1 (± 2 + 2)

0.085

Birth weight g, b)

1146 (± 282)

1126 (± 278)

0.507

Umbilical artery pH, b)

7.33 (± 0.30)

7.29 (± 0.09)

0.124

Apgar 1′/5′/10′, c)

7 / 8 / 8

7 / 8 / 8

0.250 / 0.144 / 0.022

Apgar 1′/5′/10′ c)

(0; 6–8; 9 / 4; 7–8; 9 / 6; 8–8; 10)

(1; 6–8; 9 / 3; 7–8; 9 / 5; 8–8; 10)

 

CRIB-Score, c)

1 (0 / 1–2 / 10)

1 (0 / 1–4 / 12)

0.548

Highest Bilirubin, μmol/l, b)

145.80 (± 28.88)

144.77 (± 33.99)

0.762

Antenatal steroids 1 dose / 2 doses, a)

87 (49) / 53 (30)

90 (54) / 46 (28)

0.478 / 0.624

Ceaseraen delivery, a)

162 (92)

151 (91)

0.589

Patent ductus arteriosus, a)

35 (20)

46 (28)

0.408

BPD, d)

15 (9)

12 (7)

0.693

Retinopathia neonatorum ≥3, d)

0

2 (1)

0.235

Intraventricular haemorrhage ≥3, d)

1 (1)

6 (4)

0.061

Periventricular leukomalacia, d)

0

2 (1)

0.235

Parental Education Score 1/2 d); 3/4 a) a

2 (1) / 10 (6) / 96 (55) / 49 (28)

1 (1) / 9 (5) / 93 (56) / 57 (34)

0.620 / 0.817 / 0.584 / 0.405

Max CrP 72 h postnatal, c)

1.04 (0 / 0–3.91 / 52.37)

1.04 (0 / 0–5.08 / 68.45)

0.748

Leukocytes in first CBC, ×109,b)

9.50 (± 5.86)

9.96 (± 7.04)

0.512

Last Maternal CrP prior to Birth, c)

6.82 (0 / 1.65–17.25 / 118.3)

7.43 (0 / 2.42–21.98 / 70.77)

0.330

PROM < 24 h a) / >  24 h e) />  1 week, a)

55 (31) / 15 (9) / 29 (16)

39 (23) / 10 (6) / 29 (17)

0.108 / 0.412 / 0.699

Chorioamnionitis, a)

21 (12)

14 (8)

0.374

LOS a)

20 (11)

36 (22)

0.427

Total sepsis symptoms c) b

3 (0 / 1–4 / 7)

3 (0 / 1–4 / 7)

0.127

  1. a) n (%), χ2-test; b) mean, SD, 1-Way ANOVA; c) median, min, IQR, max; Kruskal-Wallis-Test; d) n (%), Fisher’s exact test;
  2. adisplayed are n of individual parental education score categories as defined in the methods section
  3. bdisplayed is the median total of clinical symptoms associated with EOS as defined in the methods section
  4. Abbreviations: BPD Bronchopulmonary dysplasia, CBC Complete blood count, CRIB Clinical risk index for babies, EOS Early onset sepsis, LOS Late onset sepsis, PROM Premature rupture of membranes, WBC White blood cell count