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Table 4 Impact of Awareness of HIE Diagnosis and Treatment Guidelines

From: Neonatal hypoxic-ischemic encephalopathy diagnosis and treatment: a National Survey in China

HIE diagnostic indicators, n (%)

HIE diagnosis

P-value

Aware n = 232 (85)

Unaware n = 41

Neurological manifestations

222 (95.7)

41 (100.0)

0.366

Arterial Blood gas

167 (72.0)

19 (46.3)

0.001

Abnormal EEG/aEEG

136 (58.6)

16 (39.0)

0.02

Abnormal MRI

174 (75.0)

26 (63.4)

0.122

CT low density shadow

66 (28.4)

13 (31.7)

0.671

Blood neuroenzymatic changes

75 (32.3)

11 (26.8)

0.485

 

HIE Treatment

 

Aware n = 171 (63)

Unaware n = 102

 

Rate of TH, n (%)

98 (57.3)

49 (48.0)

0.137

Neuroprotection agents, n (%)

133 (77.8)

89 (87.3)

0.052

 

TH Protocol

 

Aware n = 129 (88)

Unaware n = 18

 

Rate of TH compliance, n (%)

37 (28.7)

2 (11.1)

0.195

  1. Abbreviation: HIE Hypoxic-ischemic encephalopathy, EEG Electroencephalography, aEEG amplitude-integrated electroencephalography, MRI Magnetic resonance imaging, CT Computerized tomography, TH Therapeutic hypothermia