Table 3 Possible predictive factors for distinguishing permanent congenital hypothyroidism based on receiver operating characteristics (ROC)

LT4 dose by weight at 1st year

0.545

0.241

> 3.91 µg/kg

48.42 %

63.29 %

LT4 dose by weight at 2nd year

0.587

0.033*

> 2.94 µg/kg

64.65 %

55.88 %

LT4 dose by weight at 3rd year

0.616

0.026*

> 2.25 µg/kg

76.11 %

58.52 %

TSH at 1st screening

0.593

< 0.001*

> 13.2 mIU/L

31.92 %

89.32 %

TSH at 2nd screening

0.578

0.002*

> 18.5 mIU/L

27.22 %

87.36 %

TSH at confirmatory venous sampling (Initial TSH)

0.625

< 0.001*

> 43.35 mIU/L

31.66 %

90.32 %