Table 2 Characteristic Features of Griscelli Syndrome
Griscelli Syndrome Type 1 | Griscelli Syndrome Type 2 | Griscelli Syndrome Type 3 | |
|---|---|---|---|
Gene involved | MYO5A | RAB27A | MLPH |
Inheritance | Autosomal recessive | Autosomal recessive | Autosomal recessive |
Albinism features | Yes | Yes | Yes |
Immune deficiency | Absent | Present | Absent |
Hemophagocytic lymphohistiocytosis | Absent | Present | Absent |
Neurological impairment | Severe (primary) | Rare (not primary) | Absent |