A multicenter evaluation of viral bloodstream detections in children presenting to the Emergency Department with suspected systemic infection

Table 1 Standard-of-care (SOC) culture results with respect to viral pathogen detections by the emvPCR test

Viral targets on emvPCR test, n(%)	Bloodstream infection (n = 29)	Urinary tract infection (n = 37)^a	Bacterial meningitis (n = 1)^b	Any SBI (n = 63)^c
Adenovirus (n = 49)	1/49 (2.0%)	1/18 (5.6%)	0/3 (0%)	1/49 (2.0%)
Cytomegalovirus (n = 33)	1/33 (3.0%)	1/13 (7.7%)	0/1 (0%)	2/33 (6.1%)
Enterovirus (n = 125)	0/125 (0%)	6/59 (10.2%)	0/13 (0%)	6/125 (4.8%)
Human parechovirus (n = 6)	1/6 (16.7%)	1/4 (25.0%)	0/2 (0%)	1/6 (16.7%)
Parvovirus B19 (n = 32)	0/32 (0%)	0/3 (0%)	0/0 (0%)	0/32 (0%)
All viral positives (n = 224)	3/224 (1.3%)	9/89 (10.1%)	0/21 (0%)	10/224 (4.5%)
All viral negatives (n = 890)	26/890 (2.9%)	28/294 (9.5%)	1/59 (1.7%)	53/890 (6.0%)
Total	29/1114 (2.6%)	37/383 (9.7%)	1/80 (1.3%)	63/1114 (5.7%)

^aDenominator represents the number of subjects who had urine cultures performed
^bDenominator represents the number of subjects who had CSF cultures performed
^cTotal number of SBIs may be less than sum of individual SBIs if individual subjects had multiple types of SBIs

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