Table 3 Univariate analysis of risk factors associated with increased mortality among patients admitted to the Pediatric Intensive Care Unit (PICU) with sepsis
Variables | Outcome | p-value | |
|---|---|---|---|
Alive n = 86 | Dead n = 27 | ||
Age group | 0.502 | ||
1 month to < 1 year | 28 (32.6%) | 8 (29.6%) | |
1 year to < 6 years | 28 (32.6%) | 12 (29.6%) | |
6 to 14 years | 30 (34.9%) | 7 (25.9%) | |
Female Gender | 41 (47.7%) | 13 (48.1%) | 0.996 |
Increase of pSOFA Score > 4 since admission | 33 (38.4%) | 18 (66.67%) | 0.012 |
Pre-existing percutaneous central line (compared to surgical line only) | 6 (7%) | 8 (29.6%) | 0.006 |
Any morbidity at admission | 61 (70.9%) | 24 (89.9) | 0.059 |
Malignancy alone as a co-morbidity | 24 (27.9%) | 9 (33.3%) | 0.589 |
Septic Shock | 39 (45.3%) | 18 (66.7%) | 0.053 |
Giving any amount of Resuscitation Fluids | 48 (55.8%) | 18 (66.7%) | 0.318 |
Ventilation (non-invasive vs. invasive only) | 41 (62.1%) | 25 (92.65%) | 0.020 |
Late administration of Antibiotics | 4 (7.5%) | 2 (7.4%) | 0.687 |
Median duration of PICU in daysa (IQR) | 8 (10) | 11 (22) | 0.031 |