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Table 1 Demographic and clinical characteristics of HIV infected children on antiretroviral therapy

From: Neurocognitive function among HIV-infected children on protease inhibitor -based versus non-protease inhibitor based antiretroviral therapy in Uganda: a pilot study

Characteristic

ART regimen

P-value

PI based (n = 34)

Non-PI based (n = 42)

 

Age in years, mean ± SD

8.5 ± 2.0

9.5 ± 1.9

0.03

Female sex, No. (%)

20 (58.8)

24 (57.1)

0.88

Child years in school, mean ± SD

5.4 ± 2.5

5.7 ± 1.8

0.52

Socioeconomic status, mean ± SD

7.4 ± 2.8

5.7 ± 3.3

0.02

BMI for age, mean ± SD

−0.6 ± 1.0

− 0.4 ± 1.1

0.45

MUAC, mean ± SD

18.4 ± 1.8

19.0 ± 1.7

0.14

Duration of ART, mean ± SD

7.8 ± 1.7

7.7 ± 1.8

0.84

Primary care giver, No. (%)

  

0.58

 Mother

24 (70.6)

32 (76.2)

 

 Others

10 (29.4)

10 (23.8)

 

Primary care giver education level, No. (%)

  

0.40a

 None

2 (4.8)

 

 Primary

16 (47.0)

21 (50.0)

 

 Secondary

14 (41.2)

11 (26.1)

 

 Tertiary

4 (11.8)

6 (14.3)

 

 Don’t know

2 (4.8)

 

WHO stage at ART initiation, No. (%)

  

0.02a

 I

18 (52.9)

9 (21.4)

 

 II

7 (20.6)

19 (45.2)

 

 III

8 (23.5)

12 (28.6)

 

 IV

1 (2.9)

2 (4.8)

 

On Co-trimoxazole prophylaxis, Yes. (%)

34 (100)

38 (90.5)

0.12a

Child born before term, No. (%)

  

0.12a

 Yes

3 (8.8)

 

 No

30 (88.2)

41 (97.6)

 

 Don’t Know

1 (2.9)

1 (2.4)

 

Age at ART initiation

  ≤ 3 years

31 (91%)

26 (62%)

 

  > 3 years

3 (9%)

16 (38%)

0.003

  1. Abbreviation: PI Protease Inhibitor.
  2. aFisher’s exact test was used to test for associations; otherwise the chi-square test was used. For continuous variables, a t test was used to test for differences in means between groups