Table 2 Comparison of Th cytokine concentrations in the different groups
From: Th cytokine profile in childhood-onset systemic lupus erythematosus
Cytokine | cSLE (n = 33) | Active cSLE (n = 17) | Inactive cSLE (n = 16) | Control (n = 30) | Pad | Pbd | Pcd | Pbc |
|---|---|---|---|---|---|---|---|---|
IL-2 | 53.11 (27.80–96.71) | 89.99 (59.49–178.10) | 28.80 (21.64–39.34) | 32.51 (16.90–53.39) | 0.047* | 0.012* | 0.395 | 0.003** |
IL-4 | 31.73 (12.20–76.14) | 14.17 (10.88–45.61) | 51.08 (15.40–126.39) | 41.28 (31.39–80.06) | 0.565 | 0.143 | 0.806 | 0.162 |
IL-5 | 5.91 (4.36–11.89) | 8.24 (4.92–13.91) | 5.07 (4.54–9.34) | 6.47 (4.83–9.53) | 0.802 | 0.537 | 0.783 | 0.619 |
IL-6 | 41.80 (19.03–126.67) | 41.80 (18.73–87.16) | 70.02 (17.72–139.57) | 36.00 (18.63–61.98) | 0.245 | 0.438 | 0.302 | 0.490 |
IL-9 | 43.24 (23.52–64.37) | 46.23 (18.00–112.15) | 43.24 (26.45–62.75) | 35.82 (16.38–76.85) | 0.438 | 0.482 | 0.912 | 0.452 |
IL-10 | 11.54 (4.80–29.82) | 13.30 (9.98–33.67) | 5.94 (2.97–16.25) | 5.71 (2.91–9.03) | 0.001** | 0.001** | 0.162 | 0.039* |
IL-13 | 18.29 (8.57–47.65) | 18.20 (7.30–40.57) | 18.76 (8.81–56.03) | 26.81 (16.22–46.22) | 0.253 | 0.138 | 0.739 | 0.423 |
IL-17A | 38.90 (12.18–453.90) | 94.56 (24.29–450.40) | 16.25 (11.55–458.13) | 45.42 (17.92–79.22) | 0.291 | 0.522 | 0.483 | 0.937 |
IL-17F | 17.30 (5.37–22.44) | 11.34 (4.95–21.34) | 20.52 (12.12–59.75) | 19.19 (9.95–44.56) | 0.366 | 0.235 | 0.906 | 0.249 |
IL-21 | 65.33 (29.17–176.17) | 55.07 (27.55–183.42) | 87.18 (29.17–137.60) | 18.01 (10.51–39.17) | 0.003** | 0.047* | 0.044* | 0.807 |
IL-22 | 24.11 (13.35–63.48) | 21.43 (10.02–26.28) | 37.34 (16.43–132.33) | 63.85 (30.84–133.13) | 0.217 | < 0.001** | 0.972 | 0.086 |
IFN-γ | 72.95 (16.59–227.02) | 58.80 (18.17–336.42) | 72.95 (8.96–205.93) | 69.61 (30.04–148.88) | 0.555 | 0.524 | 0.883 | 0.652 |
TNF-α | 46.95 (21.35–114.53) | 108 (25.29–131.23) | 25.03 (13.48–77.26) | 17.50 (11.68–30.65) | 0.151 | 0.150 | 0.297 | 0.877 |