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Fig. 2 | BMC Pediatrics

Fig. 2

From: Targeting human milk fortification to improve very preterm infant growth and brain development: study protocol for Nourish, a single-center randomized, controlled clinical trial

Fig. 2

Nourish study timeline of enrollment, interventions, and assessment. The study diet will start the first weekday that the infant reaches a full volume, fortified enteral diet (≥140 mL/kg/day human milk). The study diet will end at 36 weeks’ postmenstrual age (PMA). Anthro is anthropometry (weight, length, head circumference). BC is body composition assessed with air displacement plethysmography. MRI will be obtained at 38–41 weeks’ PMA. Bayley Scales of Infant and Toddler Development, 4th edition will be used. Spatial working memory will be assessed with the “Spin the Pots” task, behavioral inhibition with the “Mommies and Babies” task, and executive function and behavioral difficulties with parent questionnaires (Behavioral Rating Inventory of Executive Function – Preschool Version; and Infant-Toddler Symptom Checklist—Long Version). Ages in the follow-up phase are corrected ages (age corrected for preterm birth)

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