Table 2 Clinical characteristics of 316 children under 3 years of age with HB
n | Ratio (%) | |
|---|---|---|
Gender | ||
Male | 192 | 60.8 |
Female | 124 | 39.2 |
Age (years-old) | ||
< 1 | 128 | 40.5 |
1–3 | 188 | 59.5 |
AFP at first consultation (ng/mL) | ||
≤ 100 | 17 | 5.4 |
101–1000 | 100 | 31.6 |
1001-1000,000 | 189 | 59.8 |
> 1000,000 | 10 | 3.2 |
Platelet count at first consultation (×109/L) | ||
≤ 400 | 142 | 44.9 |
> 400 | 174 | 55.1 |
Pathological typing | ||
Epithelial type | 164 | 51.9 |
Fetal type | 61 | 37.2 |
Embryonal type | 90 | 54.9 |
combined fetal and embryonal type | 9 | 5.5 |
Small cell undifferentiated type | 4 | 2.4 |
Mixed type | 152 | 48.1 |
The PRETEXT staging system | ||
Stage I | 9 | 2.8 |
Stage II | 84 | 26.6 |
Stage III | 180 | 57.0 |
Stage IV | 43 | 13.6 |
The COG Evans staging system | ||
Stage I | 9 | 2.8 |
Stage II | 80 | 25.3 |
Stage III | 95 | 30.1 |
Stage IV | 132 | 41.8 |
Portal vein (P) invasion, Hepatic vein/vessel (V) invasion | ||
Y | 62 | 19.6 |
N | 254 | 80.4 |
extrahepatic tumor extension (E) | ||
Y | 52 | 16.5 |
N | 264 | 83.5 |
Tumor rupture (R) | ||
Y | 20 | 6.3 |
N | 296 | 93.7 |
Distant metastasis (M) | ||
Y | 132 | 41.8 |
N | 184 | 58.2 |
Multifocality (F) | ||
Y | 74 | 23.4 |
N | 242 | 76.6 |
Complete removal of the primary tumor | ||
Y | 213 | 67.4 |
N | 103 | 32.6 |