Treatment administered to newborns with congenital syphilis during a penicillin shortage in 2015, Fortaleza, Brazil

Table 1 Maternal treatment, performed tests and clinical manifestations in cases of CS. Fortaleza, Ceará, 2015. (n = 469)

Variables	Number	Percent
Maternal
Mother did not attend prenatal care	79	16.9
Mother attended prenatal care	390	83.1
Mother not diagnosed with syphilis in prenatal care	126	32.3
Mother diagnosed with syphilis in prenatal care	264	67.7
Maternal treatment in prenatal care
Inadequate treatment	204	77.3
Untreated	60	22.7
Newborn
Newborns with reactive serum VDRL result at birth (n = 467)^a	367	78.6
Newborns with serum VDRL titration at birth ≥ 1:16 (n = 367)	53	14.4
Alteration in long bone radiography (n = 139)^a	10	7.2
CSF alteration (n = 292)^a	26	8.9
Type of CSF alteration (n = 26)^b
Reactive CSF VDRL test	8	30.8
Proteins > 150 mg/dL	11	42.3
Leukocytes > 25 cells/mm³	10	38.4
Blood count alteration (n = 362)^a	159	43.9
Type of Blood count alteration (n = 159)^b
Anemia	43	27.0
Thrombocytopenia	31	19.5
Leukocytosis	83	52.2
Leukopenia	27	17.0
Showed some clinical manifestation (n = 456)	199	43.6
Type of clinical manifestation (n = 199)^b
Jaundice level requiring phototherapy	116	58.3
Low birth weight	87	43.7
Preterm birth	65	32.6
Hepatomegaly	14	7.0
Skin lesions	10	5.0
Splenomegaly	8	4.0
Limb pseudoparalysis	1	0.5

^a Data available for newborns who underwent the examination
^b Some newborns had more than one CSF alteration, blood count alteration and clinical manifestation

ISSN: 1471-2431