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Table 3 Comparisons of metabolic risk factors between obese children with NAFLD and those without liver disorder

From: Clinical characteristics and risk factors of nonalcoholic fatty liver disease in children with obesity

Factors

SOB (N = 148)

NAFLD

χ2

p-value

SS (N = 235)

NASH (N = 45)

  

Abdominal obesity

 Waist circumference (cm) ≥ p90, %

144 (97.3%)

234 (99.6%)

45 (100.0%)

4.67

0.097

Elevated blood pressure

 SBP or DBP ≥ p90, %

62 (41.9%)a

146 (62.1%)

30 (66.7%)

17.56

0.001

Dyslipidemia

 Triglycerides (mmol/L) ≥ 1.47 mmol/L, %

57 (38.5%)ab

133 (56.6%)

27 (60.%)

13.44

0.001

 HDL (mmol/L) < 1.03 mmol/L, %

15 (10.1%)b

65 (27.7%)

8 (17.8%)

17.63

0.001

Impaired fasting glucose

 Fasting Glucose ≥5.6 mmol/L, %

2 (1.4%)

6 (2.6%)

2 (4.4%)

1.55

0.460

Insulin resistance

 HOMA-IR (≥3.16), %

57 (38.5%)ab

110 (46.8%)a

31 (68.9%)

12.87

0.002

Hyperuricemia

 Uric Acid (umol/L) ≥ 357umol/L, %

68 (45.9%)ab

161 (68.5%)a

39 (86.7%)

32.63

0.001

Metabolic syndrome, %

29 (19.6%)ab

117 (49.8%)

24 (53.3%)

38.47

0.001

  1. vs. NASH group, a p < 0.001; vs. SS group, b p < 0.001
  2. SOB Simple Obese, NAFLD Nonalcoholic Fatty Liver Disease, SS Simple Steatosis, NASH Nonalcoholic Fatty Hepatitis, SBP Systolic blood pressure, DBP Diastolic blood pressure, HDL High-density lipoprotein, HOMA-IR Homeostasis model assessment of insulin resistance