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Table 1 Pulmonary function test findings in preschool children with congenital diaphragmatic hernia and healthy control groupa

From: Functional and structural evaluation in the lungs of children with repaired congenital diaphragmatic hernia

 

Case (n = 28)

Control (n = 38)

Mean difference

P-value

Male, n (%)

15 (53%)

19 (50%)

0.80

PFT ageb, years

6.2 ± 0.2

6.2 ± 0.1

0.96

FVC, liter

1.2 ± 0.1

1.5 ± 0.04

0.3 ± 0.1

< 0.001

FVC%, %

91.2 ± 2.6

107.4 ± 1.6

16.2 ± 3.1

< 0.001

FEV1, liter

1.1 ± 0.05

1.4 ± 0.04

0.3 ± 0.1

< 0.001

FEV1%, %

90.7 ± 2.7

108.4 ± 1.9

17.8 ± 3.3

< 0.001

FEV1/FVC, %

91.1 ± 1.3

92.1 ± 0.9

1.1 ± 1.6

0.50

FEF25_75%, liter/second

1.5 ± 0.1

1.9 ± 0.1

0.4 ± 0.1

< 0.01

FEF25_75%%, %

98.8 ± 5.7

103.7 ± 4.8

5.0 ± 7.5

0.50

  1. FEF25_75% maximum mid-expiratory flow, FEV1 forced expiratory volume in 1 s, FEV1/FVC FEV1 to FVC ratio, FVC functional vital capacity
  2. aChildren with left-sided congenital diaphragmatic hernia only
  3. bAge at which pulmonary function test was performed