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Table 3 Subgroup analysis infants of GDM study population with or without neonatal hypoglycemia

From: Body composition in term offspring after maternal gestational diabetes does not predict postnatal hypoglycemia

 

Study cohort GDM

No Hypoglycemia

n = 18

Study cohort GDM

≥1 Hypoglycemia

n = 17

p

Maternal characteristics

 Pre-pregnancy BMI (kg/m2)

Median (Q1, Q3)

26.0 (24.3–27.2)

29.4 (24.1–34.0)

0.10

 Gestational weight gain categoriesa

n (%)

  

0.47

  Insufficient

 

4 (22%)

6 (35%)

 

  Adequate

 

6 (33%)

2 (12%)

 

  Excessive

 

8 (44%)

9 (53%)

 

 Maternal insulin therapy

n (%)

7 (39%)

7 (41%)

1.0

Infant characteristics

 Female

n (%)

12 (67%)

6 (35%)

0.09

 Birth weight (g)

Median (Q1, Q3)

3555 (2998–3878)

3530 (3340–3750)

0.93

 SDS birth weight

Median (Q1, Q3)

0.28 (−0.33–0.90)

0.38 (−0.31–0.83)

1.0

 Blood glucose postnatal (mg/dl)

Median (Q1, Q3)

   

  0-1 h

 

67 (58–87)

49 (37–67)

0.02

  1-3 h

 

65 (58–68)

48 (40–63)

0.05

  3-6 h

 

65 (58–70)

64 (51–70)

0.60

  6-12 h

 

60 (58–67)

49 (43–66)

0.04

  12-24 h

 

69 (60–74)

55 (52–63)

0.04

 Minimal blood glucose level

Median (Q1, Q3)

55 (52–59)

36 (32–40)

< 0.0001

Infants’ body composition

 Fat mass (g)

Median (Q1, Q3)

377 (280–582)

380 (350–444)

0.73

 Fat mass / total body mass (%)

Median (Q1, Q3)

12.5 (9.3–16.0)

11.3 (10.1–13.8)

0.44

 Fat-free mass (g)

Median (Q1, Q3)

2891 (2535–3127)

2996 (2678–3251)

0.46

  1. Abbreviations: BMI body mass index, GDM gestational diabetes mellitus, SDS standard deviation score, oGTT oral glucose tolerance test
  2. aGestational weight gain categories, classified according to the Institute of Medicine recommendations 2009 taking the pre-pregnancy BMI into account