From: Association between head circumference at two years and second and fifth year cognition
Univariate analysis (n = 227) | Multivariable analysis (n = 226) | |||
---|---|---|---|---|
Predictors | Unadjusted beta co-efficientd | P value | Adjusted beta co-efficientd | P value |
Cognition domaina | ||||
Head circumference z-scores at 24 months | ||||
≥ −2 SD | ref | – | ref | – |
< − 2 to ≥ −3 SD | −0.22 (−1.13–0.69) | 0.633 | − 0.16 (− 1.07–0.75) | 0.730 |
< − 3 SD | −2.57 (− 4.15 - -0.99) | 0.002 | − 2.21 (− 3.87 - -0.56) | 0.009 |
Sex (Female) | − 0.01 (− 0.90–0.87) | 0.977 | − 0.20 (− 1.09–0.69) | 0.653 |
Mean body ironb | 0.09 (− 0.03–0.20) | 0.131 | 0.05 (− 0.06–0.17) | 0.387 |
Mean body leadc | −0.11 (− 0.19 - -0.03) | 0.009 | − 0.10 (− 0.18 - -0.02) | 0.012 |
WAMI scores | ||||
< 33rd percentile | ref | – | ref | – |
≥ 33rd percentile | 1.49 (0.55–2.42) | 0.002 | 1.25 (0.25–2.26) | 0.015 |
Mother’s cognition | 0.03 (−0.02–0.07) | 0.203 | 0.01 (− 0.04–0.05) | 0.779 |
Length for age z-scores at 24 months | 0.18 (− 0.29–0.63) | 0.466 | −0.14 (− 0.63–0.33) | 0.551 |