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Table 2 Predictors of cognitive development at 2 years of life in children of MAL-ED cohort

From: Association between head circumference at two years and second and fifth year cognition

 

Univariate analysis (n = 227)

Multivariable analysis (n = 226)

Predictors

Unadjusted beta co-efficientd

P value

Adjusted beta co-efficientd

P value

Cognition domaina

Head circumference z-scores at 24 months

   ≥ −2 SD

ref

ref

   < − 2 to ≥ −3 SD

0.22 (−1.13–0.69)

0.633

− 0.16 (− 1.07–0.75)

0.730

   < − 3 SD

−2.57 (− 4.15 - -0.99)

0.002

− 2.21 (− 3.87 - -0.56)

0.009

Sex (Female)

− 0.01 (− 0.90–0.87)

0.977

− 0.20 (− 1.09–0.69)

0.653

Mean body ironb

0.09 (− 0.03–0.20)

0.131

0.05 (− 0.06–0.17)

0.387

Mean body leadc

−0.11 (− 0.19 - -0.03)

0.009

− 0.10 (− 0.18 - -0.02)

0.012

WAMI scores

   < 33rd percentile

ref

ref

   ≥ 33rd percentile

1.49 (0.55–2.42)

0.002

1.25 (0.25–2.26)

0.015

Mother’s cognition

0.03 (−0.02–0.07)

0.203

0.01 (− 0.04–0.05)

0.779

Length for age z-scores at 24 months

0.18 (− 0.29–0.63)

0.466

−0.14 (− 0.63–0.33)

0.551

  1. aR2 for the model - 7.6%
  2. bMean body iron levels were the average of body iron measurements at 7, 15 and 24 months of age in the cohort
  3. c Mean blood lead levels were the average of blood lead levels measured at 15 and 24 months of age in the cohort
  4. d Beta co-efficient is presented along with 95% confidence interval