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Table 4 Diagnostic value of combining different methods with a real-time polymerase chain reaction as the standard

From: Comparison of different detection methods for Mycoplasma pneumoniae infection in children with community-acquired pneumonia

 

RT-PCR

Kappa

Sensitivity

Specificity

Accuracy

Youden Index

Positive

Negative

MP-RNA (SAT) + MP-IgM (PA)

 Positive

256

112

0.602

84.2%

78.7%

80.7%

62.9%

 Negative

48

414

MP-RNA (SAT) + MP-IgM (GICT)

 Positive

223

76

0.591

73.4%

85.6%

81.1%

59.0%

 Negative

81

450

MP-IgM (GICT) + MP-IgM (PA)

 Positive

237

123

0.525

78.0%

76.6%

77.2%

54.6%

 Negative

67

403

7 RNAs + MP-IgM (PA)

 Positive

250

154

0.419

82.2%

70.7%

74.9%

52.9%

 Negative

54

372

7 RNAs + MP-IgM (GICT)

 Positive

198

120

0.419

65.1%

77.2%

72.8%

42.3%

 Negative

106

406

  1. SAT simultaneous amplification and testing
  2. PA particle agglutination
  3. GICT immune colloidal gold technique