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Table 3 Comparison of clinical characteristics of the severe and mild cases

From: Analysis of clinical characteristics of severe pertussis in infants and children: a retrospective study

 

Severe cases

(n = 22)

Mild cases

(n = 162)

Gender

Male

12

90

Female

10

72

Age (months)*

2.80 ± 1.26

4.97 ± 4.30

< 3 months *

14 (63.64%)

63 (38.89%)

Not vaccinated with pertussis vaccine*

22 (100%)

98 (60.49%)

Prematurity

4(18.18%)

19(11.73%)

Low birth weight

1(4.55%)

20(12.35%)

Macrosomia

2(9.09%)

8(4.94%)

Congenital heart disease

0

5(3.09%)

Fever*

19 (86.36%)

34 (20.99%)

Severe pneumonia

22 (100%)

0

Elevated neutrophilia percentage *

15 (68.18%)

10 (6.17%)

Elevated C-reactive protein*

11 (50.00%)

20 (12.33%)

CRP value (mg/L)*

22.37±48.89

1.52±2.13

Elevated procalcitonin *

9 (40.91%))

2 (1.23%)

PCT value (ng/ml)*

1.88±4.69

0.08±0.10

Positive bacterial sputum culture*

8 (36.36%)

15 (9.26%)

Leukocyte count (× 109/L)*

35.80 ± 20.53

19.41 ± 8.59

Leukocyte count > 50× 109/L*

4 (18.18%)

0

Antibiotic usage

 Three or more antibiotics*

18 (81.82%)

8 (4.94%)

 Special-grade antibiotics*

15 (68.18%)

4 (2.47%)

Length of hospitalization (days)*

27.71 ± 11.19

14.56 ± 5.84

Cases of death

4(18.18%)

0

  1. *p<0.05, comparison between moderate and severe cases using statistical methods.