Table 1 Clinical and biochemical parameters of the case-patients included syndromic surveillance, July to December, 2015
From: Suspected paracetamol overdose in Monrovia, Liberia: a matched case–control study
Total (N = 77) | |||
|---|---|---|---|
n (%) | n (%) | ||
Characteristics | Biochemical Indices | ||
Male | 40 (52) | Hypoglycaemia | |
Age | Once | 43 (57) | |
≤1 years | 56 (73) | Continuous over 24 h | 7 (9) |
> 1–2 years | 12 (15) | AST level (n = 69) | |
> 2 years | 9 (12) | < 2 times ULN | 5 (7) |
Died | 35(46) | 2–5 times the normal range | 12 (17) |
Symptoms | > 5 times the normal range | 52 (75) | |
Hyperthermia (total) | 43(56) | AST activity > 1000 units/L | 35 (51) |
Upon admission | 26(34) | ALT activity (n = 69) | |
2nd day of hospitalisation | 5(6) | < 2 times the normal range | 11 (16) |
Continuous over 2 days | 12(16) | 2–5 times the normal range | 11 (16) |
Respiratory distress (total) | 76 (99) | > 5 times the normal range | 47 (68) |
Upon admission | 21 (27) | ALT activity > 1000 units/L | 30 (44) |
2nd day of hospitalisation | 4 (5) | ALP activity (n = 69) | |
Continued after 2 days post-admission | 51 (66) | Normal | 60 (87) |
Respiratory distress without Hypoxemia | 65 (84) | Mildly elevated < 2 times ULN | 9 (13) |
Neurological Status | Total Bilirubin concentration (n = 69) | ||
Irritable (total) | 9 (12) | Normal | 28 (41) |
Upon admission | 2 (3) | Mild Elevation | 13 (19) |
2nd day of hospitalisation (total) | 6 (8) | Elevation of (2-3 mg/dl) | 14 (20) |
Recovering | 5 (7) | Elevation of (> 3 mg/dl) | 14 (20) |
Worsening | 1 (1) | Serum Creatinine (n = 68) | |
Continuous over 2 days | 1 (1) | Normal | 7 (10) |
Lethargic (total) | 31 (40) | Elevation less than 1 mg/dl | 32 (47) |
Upon admission | 11 (14) | Elevation (1–2 mg/dl) | 16 (24) |
2nd day of hospitalisation (total) | 10 (13) | Elevation (> = 2 mg/dl) | 13 (19) |
Recovering | 4 (5) | Estimated Anion Gap > 18 mmol/L (n = 66) | 44 (67) |
Worsening | 6 (8) | Elevated Blood Urea Nitrogen | 30 (43) |
Continuous over 2 days | 10 (13) | Malaria (RDT) | 16 (21) |
Coma (total) | 28 (36) | HIV positive (n = 45) | 3 (7) |
Upon admission | 10 (13) | ||
Decreasing GCS | 8 (10) | ||
Continuous over 2 days | 10 (13) | ||
Hepatomegaly | 57 (74) | ||
Tachycardia | 53 (68) | ||
Upon admission | 24 (31) | ||
2nd day of hospitalisation | 9 (12) | ||
Continued after 2 days of admission | 20 (26) | ||
Convulsions | 26 (34) | ||
Severe Acute Malnutrition | 19 (25) | ||