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Table 2 Variables in the management/results associated with all patients 0–36 months of age presenting to the ED with fever, previously on and off antibiotics

From: Comparing febrile children presenting on and off antibiotics to the emergency department: a retrospective cohort study

Management & resultsAll
N = 753
AB-
N = 584
AB+
N = 169
P-Value
Any blood work, yes359 (47.7)263 (45.0)96 (56.8)0.01
 Blood WBC, mean(±SD)13,468 ± 636313,324 ± 631813,865 ± 65020.48
 Blood Neutrophils, mean(±SD)53.1 ± 17.052.50 ± 16.9354.58 ± 17.070.30
 Blood Bands, mean(±SD)0.7 ± 4.30.86 ± 4.970.09 ± 0.650.02
 Blood lymphocytes, mean(±SD)36.0 ± 16.136.48 ± 16.0834.81 ± 16.240.39
 Blood CRP, mean(±SD)52.3 ± 68.752.35 ± 70.2152.03 ± 65.110.97
Bacteremia (n = 156 for blood cultures)4 (2.6)2 (1.8)2 (4.7)0.31
Any urine test done, yes168 (22.3)133 (22.8)35 (20.7)0.57
 Urine LE -positive44 (27.3)41 (31.8)3 (9.4)0.01
 Urine Nitrites -positive16 (9.9)15 (11.6)1 (3.1)0.20
 Urine bacteria -positive29 (19.0)25 (20.7)4 (12.5)0.30
 Urine WBC -positive33 (20.4)31 (23.8)2 (6.3)0.03
UTI (n = 156 for urine cultures)40 (25.6)36 (28.8)4 (12.9)0.07
CXR done, yes207 (27.5)144 (24.7)63 (37.3)0.001
Positive/probable for pneumonia110 (53.1)73 (50.7)37 (58.7)0.25
Any CSF tested, yes37 (4.9)37 (6.3)0 (0.0)0.001
 CSF WBC -positive7 (25.9)7 (25.9)0 (0.0)NA
CSF culture -positive2 (5.9)2 (5.9)0 (0.0)NA
Throat culture done, yes59 (7.8)39 (6.7)20 (11.8)0.03
 Throat culture - positive4 (3.0)4 (3.5)0 (0.0)1.00
Stool studies, yes68 (9.0)46 (7.9)22 (13.0)0.04
 Stool culture -positive1 (5.3)1 (5.3)0 (0.0)NA
Nasopharynx, yes94 (16.1)94 (16.1)0 (0.0)NA
 RSV -positive15 (34.1)12 (36.4)3 (27.3)0.72
 Flu -positive13 (21.3)13 (28.3)0 (0.0)0.03
None of the above testing donea266 (35.3)212 (36.3)54 (32.0)0.30
 At least 1487 (64.7)372 (63.7)115 (68.0)
None tested for SBIb543 (72.1)427 (73.1)116 (68.6)0.25
 At least 1 for SBI210 (27.9)157 (26.9)53 (31.4)
Fluid bolus 20 ml/Kg, yes82 (11.1)60 (10.5)22 (13.0)0.35
Admission154 (20.5)121 (20.7)34 (19.5)0.74
  1. atesting done to look for signs of SBI or other infectious causes; WBC White blood cells, LE Leukocyte Esterase, UTI Urinary tract infection, CXR Chest Radiography, CSF cerebrospinal fluid
  2. bBlood culture done, or Urine culture done, or CSF culture done
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