Table 4 Correlations of ghrelin, adiponectin and leptin with other investigated parameters in the groups of obese hypertensive patients, patients with mildly elevated lipids and normal-weight patients with hypertension (r and p values are presented)
Obese patients with hypertension | Patients with mildly elevated lipids | Normal-weight patients with hypertension | |||||||
|---|---|---|---|---|---|---|---|---|---|
Parameter/Correlation coefficient r (p-value) | Ghrelin | Adiponectin | Leptin | Ghrelin | Adiponectin | Leptin | Ghrelin | Adiponectin | Leptin |
Age (years) | -0.452 (p<0.001) | -0.519 (p<0.001) | 0.132 (p=0.212) | -0.633 (p<0.001) | -0.562 (p<0.001) | 0.407 (p<0.001) | -0.585 (p<0.001) | -0.492 (p<0.001) | 0.059 (p=0.555) |
Body weight (kg) | -0.486 (p<0.001) | -0.516 (p<0.001) | 0.219 (p=0.037) | -0.638 (p<0.001) | -0.583 (p<0.001) | 0.567 (p<0.001) | -0.577 (p<0.001) | -0.556 (p<0.001) | 0.048 (p=0.630) |
Body height (cm) | -0.496 (p<0.001) | -0.535 (p<0.001) | 0.059 (p=0.578) | -0.643 (p<0.001) | -0.575 (p<0.001) | 0.375 (p<0.001) | -0.622 (p<0.001) | -0.492 (p<0.001) | -0.097 (p=0.329) |
BMI (kg/m²) | -0.433 (p<0.001) | -0.467 (p<0.001) | 0.463 (p<0.001) | -0.577 (p<0.001) | -0.568 (p<0.001) | 0.685 (p<0.001) | -0.475 (p<0.001) | -0.508 (p<0.001) | 0.371 (p<0.001) |
Waist circumference (cm) | -0.453 (p<0.001) | -0.498 (p<0.001) | 0.287 (p=0.007) | -0.634 (p<0.001) | -0.576 (p<0.001) | 0.610 (p<0.001) | -0.587 (p<0.001) | -0.561 (p<0.001) | 0.172 (p=0.092) |
Hip circumference (cm) | -0.526 (p<0.001) | -0.519 (p<0.001) | 0.350 (p=0.001) | -0.668 (p<0.001) | -0.582 (p<0.001) | 0.618 (p<0.001) | -0.637 (p<0.001) | -0.489 (p<0.001) | 0.149 (p=0.174) |
Systolic blood pressure (mmHg) | -0.407 (p<0.001) | -0.312 (p=0.003) | -0.202 (p=0.055) | -0.387 (p<0.001) | -0.319 (p=0.002) | 0.182 (p=0.078) | -0.264 (p=0.007) | -0.188 (p=0.049) | -0.056 (p=0.571) |
Diastolic blood pressure (mmHg) | -0.139 (p=0.188) | 0.084 (p=0.429) | -0.086 (p=0.419) | -0.353 (p=0.001) | -0.345 (p=0.001) | 0.336 (p=0.001) | 0.041 (p=0.680) | 0.184 (p=0.061) | 0.085 (p=0.390) |
Ghrelin (pg/ml) | / | 0.376 (p<0.001) | -0.035 (p=0.744) | / | 0.483 (p<0.001) | -0.391 (p<0.001) | / | 0.420 (p<0.001) | -0.141 (p=0.154) |
Adiponectin (ng/ml) | 0.376 (p<0.001) | / | -0.105 (p=0.326) | 0.483 (p<0.001) | / | -0.266 (p=0.011) | 0.420 (p<0.001) | / | 0.000 (p=0.999) |
Leptin (pg/ml) | -0.035 (p=0.744) | -0.105 (p=0.326) | / | -0.391 (p<0.001) | -0.266 (p=0.011) | / | -0.141 (p=0.154) | 0.000 (p=0.999) | / |
Glucose (mmol/l) | -0.150 (p=0.165) | -0.072 (p=0.510) | 0.114 (p=0.292) | 0.010 (p=0.926) | -0.066 (p=0.544) | -0.032 (p=0.759) | -0.298 (p=0.002) | -0.021 (p=0.832) | 0.178 (p=0.074) |
Total cholesterol (mmol/l) | -0.123 (p=0.247) | 0.073 (p=0.496) | -0.068 (p=0.522) | 0.174 (p=0.114) | 0.409 (p<0.001) | -0.045 (p=0.663) | 0.097 (p=0.330) | 0.204 (p=0.039) | 0.273 (p=0.005) |
Triglycerides (mmol/l) | -0.185 (p=0.08) | -0.144 (p=0.180) | 0.015 (p=0.890) | -0.097 (p=0.379) | -0.240 (p=0.022) | 0.075 (p=0.463) | -0.257 (p=0.009) | -0.174 (p=0.078) | 0.411 (p<0.001) |
HDL cholesterol (mmol/l) | 0.311 (p=0.003) | 0.422 (p<0.001) | 0.00 (p=0.997) | 0.216 (p=0.049) | 0.413 (p<0.001) | -0.173 (p=0.089) | 0.216 (p=0.028) | 0.421 (p<0.001) | 0.066 (p=0.504) |
LDL cholesterol (mmol/l) | -0.174 (p=0.102) | -0.086 (p=0.424) | -0.031 (p=0.768) | 0.065 (p=0.561) | 0.332 (p=0.001) | 0.009 (p=0.929) | 0.026 (p=0.792) | 0.068 (p=0.498) | 0.170 (p=0.087) |
Apolipoprotein A1 (g/l) | 0.182 (p=0.1) | 0.366 (p=0.001) | -0.051 (p=0.648) | 0.145 (p=0.201) | 0.351 (p=0.001) | -0.083 (p=0.435) | 0.203 (p=0.048) | 0.387 (p<0.001) | 0.185 (p=0.072) |
Homocysteine (μmol/l) | -0.276 (p=0.011) | -0.277 (p=0.012) | -0.098 (p=0.383) | -0.238 (p=0.222) | -0.310 (p=0.108) | -0.079 (p=0.690) | -0.360 (p<0.001) | -0.393 (p<0.001) | 0.183 (p=0.080) |