TY - JOUR AU - Shaw, Alexander G. AU - Cornwell, Emma AU - Sim, Kathleen AU - Thrower, Hannah AU - Scott, Hannah AU - Brown, Joseph C. S. AU - Dixon, Ronald A. AU - Kroll, J. Simon PY - 2020 DA - 2020/02/18 TI - Dynamics of toxigenic Clostridium perfringens colonisation in a cohort of prematurely born neonatal infants JO - BMC Pediatrics SP - 75 VL - 20 IS - 1 AB - Clostridium perfringens forms part of the human gut microbiota and has been associated with life-threatening necrotising enterocolitis (NEC) in premature infants. Whether specific toxigenic strains are responsible is unknown, as is the extent of diversity of strains in healthy premature babies. We investigated the C. perfringens carrier status of premature infants in the neonatal intensive care unit, factors influence this status, and the toxic potential of the strains. SN - 1471-2431 UR - https://doi.org/10.1186/s12887-020-1976-7 DO - 10.1186/s12887-020-1976-7 ID - Shaw2020 ER -