From: Cognitive function in metformin exposed children, born to mothers with PCOS – follow-up of an RCT
Metformin (n = 52) | Placebo (n = 41) | p-value | |
---|---|---|---|
WPPSI-III/WISC-IV score | |||
Full-scale IQ mean (SD) | 100.0 (13.2) | 100.9 (10.1) | .731 |
n (%) | n (%) | .039 | |
FIQ < 70 | 0 | 0 | |
FIQ 70–84 | 9 (17.3) | 1 (2.4) | |
FIQ > 84 | 43 (82.7) | 40 (97.6) | |
Indices | |||
Verbal comprehension (SD) | 99.1 (15.6) | 99.6 (14.3) | .887 |
Working memory (SD) | 93.9 (14.8) | 96.5 (10.8) | .323 |
Perceptual organization (SD) | 107.3 (15.1) | 108.2 (13.8) | .759 |
Processing speed (SD) | 101.1 (19.7) | 98.1 (12.9) | .397 |