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Table 1 Comparison of demographic and clinical data between the control and mPCR group

From: Comparison of antibiotic and acyclovir usage before and after the implementation of an on-site FilmArray meningitis/encephalitis panel in an academic tertiary pediatric hospital: a retrospective observational study

 Control group (n = 46)mPCR group (n = 46)p value
Age (m)3.1 (1.1–22.1)2.8 (1.2–24.5) 
Sex: male27/46 (58.7%)26/46 (56.5%)1.000
Weight (kg)6.1 (4.3–11.6)6.0 (4.4–11.9)0.903
LOS (d)5.0 (5.0–6.0)5.0 (4.0–7.0)0.384
ICU10/46 (21.7%)11/46 (23.9%)1.000
CNS infections5/46 (10.9%)14/46 (30.4%)0.038
CRP (mg/dl)0.6 (0.1–1.7)0.8 (0.3–2.2)10.267
Leucocytes (G/L)8.4 (6.3–14.0)9.0 (7.2–14.1)20.577
IL-6 (pg/ml)30.0 (14.9–63.7)350.1 (10.2–106.5)40.401
CSF samples analyzed36/46 (78.3%)33/46 (71.7%) 
Cell count (/μl)2.0 (1.0–5.5)2.0 (1.0–6.0)0.522
Protein (mg/dl)34.4 (19.4–53.7)33.3 (17.6–56.2)0.936
Glucose (mg/dl)56.6 (52.0–69.6)56.7 (50.5–66.0)0.893
  1. The exact Mann-Whitney-U-Test was used to compare distributions of quantitative variables between independent groups and the Fisher’s exact test for categorical variables. Quantitative data are described by median (M) and interquartile range (IQR). Categorical data are presented as absolute number/ total (percentage) [n/N (%)]
  2. Abbreviations: multiplex PCR (mPCR), months (m), days (d), length of stay (LOS), intensive care unit (ICU), central nervous system (CNS), C-reactive protein (CRP), Interleukin-6 (IL-6), cerebrospinal fluid (CSF)
  3. Data available for 1 45 patients, 2 43 patients, 3 34 patients, 4 32 patients