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Table 1 Comparison of demographic and clinical data between the control and mPCR group

From: Comparison of antibiotic and acyclovir usage before and after the implementation of an on-site FilmArray meningitis/encephalitis panel in an academic tertiary pediatric hospital: a retrospective observational study

 

Control group (n = 46)

mPCR group (n = 46)

p value

Age (m)

3.1 (1.1–22.1)

2.8 (1.2–24.5)

 

Sex: male

27/46 (58.7%)

26/46 (56.5%)

1.000

Weight (kg)

6.1 (4.3–11.6)

6.0 (4.4–11.9)

0.903

LOS (d)

5.0 (5.0–6.0)

5.0 (4.0–7.0)

0.384

ICU

10/46 (21.7%)

11/46 (23.9%)

1.000

CNS infections

5/46 (10.9%)

14/46 (30.4%)

0.038

CRP (mg/dl)

0.6 (0.1–1.7)

0.8 (0.3–2.2)1

0.267

Leucocytes (G/L)

8.4 (6.3–14.0)

9.0 (7.2–14.1)2

0.577

IL-6 (pg/ml)

30.0 (14.9–63.7)3

50.1 (10.2–106.5)4

0.401

CSF samples analyzed

36/46 (78.3%)

33/46 (71.7%)

 

Cell count (/μl)

2.0 (1.0–5.5)

2.0 (1.0–6.0)

0.522

Protein (mg/dl)

34.4 (19.4–53.7)

33.3 (17.6–56.2)

0.936

Glucose (mg/dl)

56.6 (52.0–69.6)

56.7 (50.5–66.0)

0.893

  1. The exact Mann-Whitney-U-Test was used to compare distributions of quantitative variables between independent groups and the Fisher’s exact test for categorical variables. Quantitative data are described by median (M) and interquartile range (IQR). Categorical data are presented as absolute number/ total (percentage) [n/N (%)]
  2. Abbreviations: multiplex PCR (mPCR), months (m), days (d), length of stay (LOS), intensive care unit (ICU), central nervous system (CNS), C-reactive protein (CRP), Interleukin-6 (IL-6), cerebrospinal fluid (CSF)
  3. Data available for 1 45 patients, 2 43 patients, 3 34 patients, 4 32 patients