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Table 5 Multivariable analysis for the association variables discriminating non-irradiated survivors with disease-free both eyes

From: Survival and ocular preservation in a long-term cohort of Japanese patients with retinoblastoma

Variables

Odds ratio

95% confidence interval lower-upper limit

P-value

Neoadjuvant chemotherapy

44.4

3.65–540

0.0029

Positive family historya

13.1

1.06–162

0.045

Unilateral RB at diagnosis

7.32

0.68–84.2

0.11

male

2.63

0.35–19.9

0.35

  1. Survivors in whom both eyes were disease-free (n = 7) vs. others (n = 83) who received enucleation
  2. or external beam radiotherapy (n = 26)
  3. aEither parents or sibling(s) received a diagnosis of retinoblastoma