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Table 2 Changes in methylation fraction of CpG sites of the TERT promoter in children with obesity

From: Association of telomere length and telomerase methylation with n-3 fatty acids in preschool children with obesity

CpG sites

Obese (n=46)

Control (n=46)

t

P

1

0.71±0.05

0.70±0.03

0.773

0.4414

2

0.72±0.05

0.71±0.03

1.864

0.0653

3

0.46±0.08

0.45±0.03

1.152

0.2523

4

0.72±0.06a

0.70±0.03

2.434

0.0168

5

0.60±0.07

0.59±0.04

0.696

0.4878

6

0.33±0.06

0.32±0.05

1.034

0.3038

7

0.50±0.05

0.49±0.04

1.747

0.0838

8

0.55±0.06

0.54±0.04

1.757

0.0822

9

0.54±0.08a

0.51±0.04

2.207

0.0454

10

0.63±0.06a

0.60±0.03

2.745

0.0072

11

0.58±0.08a

0.55±0.04

2.434

0.0168

12

0.66±0.05a

0.64±0.04

2.023

0.0458

13

0.27±0.08

0.26±0.04

1.010

0.3151

14

0.56±0.08a

0.52±0.04

3.030

0.0310

15

0.38±0.07a

0.35±0.04

2.375

0.0196

16

0.41±0.09a

0.38±0.04

2.241

0.0270

17

0.31±0.09a

0.27±0.04

2.701

0.0082

18

0.34±0.10

0.31±0.04

1.956

0.0533

19

0.47±0.10a

0.43±0.05

2.869

0.0051

20

0.39±0.12a

0.33±0.04

2.946

0.0041

21

0.40±0.09

0.37±0.04

1.955

0.0535

22

0.21±0.09a

0.18±0.03

2.894

0.0048

23

0.23±0.14a

0.17±0.06

2.929

0.0044

24

0.36±0.12

0.33±0.06

1.071

0.2872

25

0.19±0.11

0.16±0.06

1.473

0.1447

Average

0.47±0.06a

0.44±0.03

0.405

0.0010

  1. aSignificant differences between the obese and control children