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Table 5 Comparison of the present study with Galand et al.’ and Filippi et al.’ results

From: Vancomycin-lock therapy for prevention of catheter-related bloodstream infection in very low body weight infants

  Galand et al.’ study
(Prospective, RCT)
Filippi et al.’ study
(Prospective, RCT)
Present study
(Retrospective study)
Gestational age, Wk 27 ± 3.8 29 ± 4.8 30 ± 1.9
Birth weight, Kg 1.1 ± 0.72 1.0 ± 0.61 1.3 ± 0.18
PICC time, d 20.3 ± 11.4 7.5 (2–29) 33.0 ± 12.7
CRBSI in AL (n/%) 4.8% (2/42) 6.0% (3/50) 4.4% (3/68)
CRBSI in C (n/%) 30.2% (13/43) 24.5% (13/53) 21.7% (15/69)
P value 0.002 < 0.01 0.004
  1. RCT randomized controlled trial, AL antibiotic-lock group, C control treatment without antibiotic-lock. P value showed the comparison between the incidence rate of CRBSI in AL and C groups