| |
Vancomycin-lock group (n = 68)
|
Control group (n = 69)
|
p value
|
|---|
|
Gender (male, n (%))
|
42 (61.8)
|
34 (49.3)
|
0.170*
|
|
Gestational age, Wk
|
29.8 ± 1.90
|
30.1 ± 2.33
|
0.323
|
|
Birth weight, Kg
|
1.2 ± 0.19
|
1.3 ± 0.23
|
0.765
|
|
5-min APGAR score
|
8.29 ± 1.04
|
8.7 ± 0.71
|
0.010
|
|
Comorbilities
|
|
Neonatal sepsis, n (%)
|
43 (63.2)
|
42 (60.9)
|
0.861*
|
|
NRDS, n (%)
|
46 (67.6)
|
44 (63.8)
|
0.720*
|
|
PDA, n (%)
|
30 (44.1)
|
31 (44.9)
|
1.000*
|
|
IVH, n (%)
|
11 (16.2)
|
16 (23.2)
|
0.391*
|
|
NEC, n (%)
|
6 (8.8)
|
7 (10.1)
|
1.000*
|
|
Meningitis, n (%)
|
4 (5.9)
|
15 (21.7)
|
0.012*
|
|
PROM time, h
|
40.2 ± 114
|
45.3 ± 92.9
|
0.776
|
|
MV time, d
|
12.8 ± 13.1
|
17.0 ± 17.9
|
0.115
|
|
PICC time, d
|
33.0 ± 12.7
|
33.7 ± 19.6
|
0.798
|
|
TPN or PPN time, d
|
35.2 ± 15.7
|
33.9 ± 17.8
|
0.660
|
|
Hospital stay, d
|
48.3 ± 16.6
|
51.8 ± 28.2
|
0.376
|
|
Hospitalization costs, RMB (Yuan)
|
110,000 ± 53,000
|
118,000 ± 80,000
|
0.491
|
- Note: *showed chi-square test, and other analysis was t-test; NRDS neonatal respiratory distress syndrome, PDA patent ductus arteriosus, IVH intraventricular hemorrhage, NEC necrotizing enterocolitis, PROM premature rupture of membrane, MV mechanical ventilation, PICC peripherally inserted central catheters, TPN total parenteral nutrition, PPN part parenteral nutrition
