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Table 3 The top 6 TFs with the most downstream regulatory genes and their target genes

From: Identification of pathogenic genes and transcription factors in respiratory syncytial virus

TF Number of regulated genes Regulated genes
Pax-4 24 PAFAH2, FCRL3, FCER1A, IFI6, TLR5, MEF2D, IFI44, OTOF, SHISA5, GYG1, LMNB1, LY6E, RALGPS1, IFITM3, TCTN1, GPR84, EPSTI1, IFI27, RPS6KA5, PPP1R13B, LUC7L, FBL, EEF2, EIF3L
1-Oct 19 FCGR1A, FCGR1B, MEF2D, FCRL3, FCER1A, IFI44, GYG1, SHISA5, LMNB1, ARG1, LY6E, RALGPS1, CRY2, KLRB1, GPR84, EPSTI1, PPP1R13B, STXBP2, EEF2
Nkx2–5 18 MEGF6, IFI44, IFI44L, GYG1, SHISA5, LMNB1, ARG1, LRCH4, RALGPS1, TCTN1, GPR84, EPSTI1, IFI27, PPP1R13B, LUC7L, RETN, GLTSCR2, EIF3L
HNF-4 16 PAFAH2, MEF2D, IFI6, TLR5, MEGF6, OTOF, GYG1, SHISA5, SERPINB1, RALGPS1, KLRB1, EPSTI1, IFI27, PPP1R13B, RPL18, EEF2
COMP1 13 PAFAH2, FCGR1A, FCGR1B, FCRL3, MEGF6, FCER1A, GLS, SHISA5, LMNB1, GPR84, EPSTI1, PPP1R13B, RPL18
Pax-6 13 FCER1A, TLR5, IFI44L, GLS, OTOF, GYG1, ARG1, LRCH4, RALGPS1, EPSTI1, RETN, EEF2, GLTSCR2