Table 3 Linear regression of correlates of thymus area at admission among 388 children with SAM
Univariate regression | Age and sex adjusted regression | ||||
|---|---|---|---|---|---|
N a | β (95% CI) b | p | β (95% CI) b | p | |
Male sex | 388 | 0.01 (-0.07; 0.10) | 0.79 | 0.01 (-0.07; 0.10) | 0.78 |
Age, months | 388 | 0.001(-0.004; 0.01) | 0.76 | 0.001 (-0.004; 0.01) | 0.75 |
Anthropometry at admission | |||||
Weight, kg | 382 | 0.03 (0.01; 0.06) | 0.01 | 0.06 (0.02; 0.09) | 0.001 |
Length, cm | 379 | 0.01 (1.03; 0.01) | 0.05 | 0.02 (0.004; 0.03) | 0.01 |
MUAC, cm | 382 | 0.03 (0.001; 0.06) | 0.046 | 0.03 (0.0003; 0.06) | 0.048 |
Weight-for-length, z-score | 380 | 0.03 (0.01; 0.06) | 0.02 | 0.03 (0.04; 0.06) | 0.02 |
Length-for-age, z-score | 380 | 0.04 (0.01; 0.07) | 0.02 | 0.05 (0.02; 0.08) | 0.003 |
Clinical history | |||||
Severity of sickness VASc | 387 | -0.01 (-0.03; 0.01) | 0.49 | − 0.01 (-0.03; 0.01) | 0.47 |
Sick for > 2 weeks | 377 | -0.10 (-0.19; -0.01) | 0.03 | -0.10 (-0.19; -0.01) | 0.03 |
Cough | 387 | 0.02 (-0.06; 0.11) | 0.60 | 0.02 (-0.06; 0.11) | 0.60 |
Fever | 387 | -0.003 (-0.09; 0.08) | 0.95 | -0.003 (-0.09; 0.08) | 0.95 |
Examination | |||||
Oedema | 388 | -0.06 (-0.15; 0.03) | 0.19 | -0.06 (-0.15; 0.03) | 0.16 |
Skin hypopigmentation | 388 | -0.04 (-0.13; 0.04) | 0.34 | -0.04( -0.13; 0.04) | 0.33 |
Dermatosis | 388 | -0.15 (-0.31; 0.01) | 0.07 | -0.15 (-0.31; 0.01) | 0.07 |
Hair depigmentation | 383 | -0.10 (-0.19; 0.001) | 0.05 | -0.10 (-0.20; 0.0002) | 0.05 |
Oral thrush g | 387 | 0.01 (-0.09; 0.11) | 0.80 | 0.01 (-0.09; 0.11) | 0.80 |
Diagnosis | |||||
Diarrhoea | 387 | -0.03 (-0.12; 0.05) | 0.48 | -0.03 (-0.12; 0.06) | 0.50 |
Pneumonia | 388 | 0.04 (-0.07; 0.22) | 0.49 | 0.04 (-0.07; 0.15) | 0.49 |
Suspected tuberculosis | 388 | 0.12 (0.01; 0.2) | 0.03 | 0.12 (0 0.01; 0.22) | 0.03 |
Suspected septicaemia | 386 | 0.08 (-0.02; 0.18) | 0.12 | 0.08 (-0.02; 0.18) | 0.12 |
Child HIV status | 367 | ||||
Negative | - | - | - | - | |
Positive | -0.08 (-0.22; 0.05) | 0.21 | -0.08 (-0.22; 0.05) | 0.22 | |
Exposed, negative | -0.01 ( -0.12; 0.10) | 0.80 | -0.01 ( -0.12; 0.10) | 0.80 | |
C-reactive protein, mg/L | 343 | ||||
< 5 | - | - | - | - | |
5–15 | -0.01 (-0.14, 0.11) | 0.85 | -0.01 (-0.14, 0.11) | 0.85 | |
> 15 | -0.03 (-0.14, 0.08) | 0.60 | -0.03 ( -0.14, 0.08) | 0.59 | |
Leukocytes, X109/L, | |||||
Neutrophils > 9 | 293 | 0.13 (-0.02; 0.28) | 0.08 | 0.13 (-0.02; 0.28) | 0.08 |
Lymphocytes > 10 | 293 | 0 0.12 (-0.05; 0.30) | 0.17 | 0.13 (-0.05; 0.30) | 0.16 |
Haemoglobin, g/dl | 292 | -0.001 (-0.03; 0.02) | 0.96 | -0.001 (-0.03; 0.02) | 0.97 |
Breastfed | 384 | ||||
Previously | - | - | - | - | |
Currently | 0.13 ( 0.01, 0.25) | 0.04 | 0.14 ( 0.01, 0.26) | 0.03 | |
Never | -0.09 ( -0.37; 0.18) | 0.50 | -0.09 ( -0.37; 0.18) | 0.50 | |
Mother | |||||
Lives with child | 388 | 0.09 (-0.02; 0.19) | 0.11 | 0.09 (-0.02; 0.19) | 0.10 |
Education: | 384 | ||||
Post primary | - | - | - | - | |
≤primary | 0.06 (-0.03; 0.14) | 0.19 | 0.05 (-0.03; 0.14) | 0.20 | |