Table 2 Vital signs over time (6-hour intervals) post benzodiazepine treatment (n = 30)

Heart rate^a

Lorazepam

130 [110, 150]

(90, 160)

112 [110, 128]

(100, 140)

110 [102, 112]

(90, 120)

102 [100, 112]

(88, 130)

100 [99, 110]

(80, 126)

T0 vs. T24

T6 vs. T24

T0 vs. T18

Clonazepam

120 [100, 140]

(92, 144)

115[106, 122]

(100, 148)

107 [100, 110]

(80, 127)

110 [97, 119]

(88, 123)

108 [98, 120]

(88, 120)

Temperature^a

Lorazepam

37 [36.6, 37]

(36, 37.1)

37 [36.9, 37]

(36.7, 37.8)

36.8 [36.5, 37]

(36.2, 37.5)

36.8 [36.5, 37]

(36.2, 37.5)

36.5 [36.5, 36.8]

(36.2, 37)

T6 vs. T24

Clonazepam

37 [36.6, 37]

(36, 37.2)

37 [36.9, 37]

(36.5, 37)

36.8 [36.5, 37]

(36, 37.2)

37 [36.5, 37]

(36.5, 37.2)

36.5 [36.5, 36.9]

(36.5, 37)

-

Respiratory rate^a

Lorazepam

30 [26, 35]

(20, 60)

25 [22, 27]

(20 ,55)

25 [22, 25]

(18 ,50)

23 [22, 26]

(20 ,26)

22 [22, 24]

(21 ,25)

T0 vs. T12

T6 vs. T24

Clonazepam

30 [24, 33]

(16, 60)

29 [20, 32]

(20 ,40)

25 [21, 29]

(18 ,35)

25 [21, 29]

(18 ,30)

24 [19, 25]

(18 ,30)

T0 vs. T24

T6 vs. T24

Systolic blood pressure^a

Lorazepam

92 [90, 100]

(80, 100)

92 [90, 90]

(80, 100)

90 [80, 97]

(80, 100)

90 [75, 100]

(70, 100)

90 [77, 92]

(70, 100)

-

Clonazepam

90 [90, 100]

(80, 110)

90 [90, 100]

(80, 110)

85 [80, 90]

(80, 100)

85 [80, 85]

(70, 90)

75 [70, 75]

(70, 100)

-