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Table 2 Observed number of cases of autism spectrum disorder (ASD) both for the cohort as a whole (n = 92) and according to maternal iodine-to-creatinine ratio (I:Cr). In addition to the modelled predicted probability of a diagnosis of ASD (95% CIs) at the 25th, 50th and 75th centiles of I:Cr, for ‘average’ participantsa

From: Maternal iodine status in a multi-ethnic UK birth cohort: associations with autism spectrum disorder

Iodine-to-creatinine ratio
I:Cr (μg/g), median (range)
(n) Observed cases of autism spectrum disorder (ASD) (n) (percent) Probability of a diagnosis of autism spectrum disorder (percent) (95%CIs)
All participants: 6973 92 (1·3%)  
Lower third: 59·5, (0·7 to 67) 2325 28 (1·2%) 1·0 (0·3 to 1·7)
Middle third: 83·1, (67 to 105) 2324 27 (1·2%) 1·1 (0·4 to 1·8)
Higher third: 121·9, (> 105) 2324 37 (1·6%) 1·5 (0·5 to 2·4)
  1. a ‘Average’ participants were specified according to the largest categories or mean cohort values. Predicted estimates represent an average birth, not specified by child’s sex - related to participants who are primiparous, white ethnic background, ‘Employed and not materially deprived’, did not smoke, drink, were of mean age and an average BMI