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Table 2 Observed number of cases of autism spectrum disorder (ASD) both for the cohort as a whole (n = 92) and according to maternal iodine-to-creatinine ratio (I:Cr). In addition to the modelled predicted probability of a diagnosis of ASD (95% CIs) at the 25th, 50th and 75th centiles of I:Cr, for ‘average’ participantsa

From: Maternal iodine status in a multi-ethnic UK birth cohort: associations with autism spectrum disorder

Iodine-to-creatinine ratio

I:Cr (μg/g), median (range)

(n)

Observed cases of autism spectrum disorder (ASD) (n) (percent)

Probability of a diagnosis of autism spectrum disorder (percent) (95%CIs)

All participants:

6973

92 (1·3%)

 

Lower third: 59·5, (0·7 to 67)

2325

28 (1·2%)

1·0 (0·3 to 1·7)

Middle third: 83·1, (67 to 105)

2324

27 (1·2%)

1·1 (0·4 to 1·8)

Higher third: 121·9, (> 105)

2324

37 (1·6%)

1·5 (0·5 to 2·4)

  1. a ‘Average’ participants were specified according to the largest categories or mean cohort values. Predicted estimates represent an average birth, not specified by child’s sex - related to participants who are primiparous, white ethnic background, ‘Employed and not materially deprived’, did not smoke, drink, were of mean age and an average BMI