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Table 7 Results for the combinations of metabolites from all subsets (i-iv) with lowest errors

From: Altered metabolism of mothers of young children with Autism Spectrum Disorder: a case control study

Subset

Combination

Type I Error

Type II Error

(i): FOCM/TS Metabolites

tCysteine, Glu-Cys, fCysteine, fCystine/fCystiene, Nitrotyrosine

24%

27%

(ii): FOCM/TS metabolites plus nutritional information

SAM/SAH, Glu-Cys, GSSG, fCysteine, B12

24%

27%

(iii): FOCM/TS metabolites, nutritional information, and MTHFR gene information

SAM/SAH, tCysteine, Glu-Cys, B12, MTHFR mut. (A1298C)

24%

20%

(iv): FOCM/TS metabolites, nutritional information, MTHFR gene information, and Metabolon metabolites

Glu-Cys, histidylglutamate, cinnamoylglycine, proline, adrenoylcarnitine (C22:4)a

3%

3%

  1. The a indicates metabolites measured by Metabolon that were not officially confirmed based on a standard, but Metabolon is confident of the Metabolite’s identity