Altered metabolism of mothers of young children with Autism Spectrum Disorder: a case control study

BMC Pediatrics

Table 3 Current mental and physical symptoms of mothers. The severity scale was 0 = none, 1 = mild, 2 = moderate, 3 = severe. The mean is listed with the standard deviation in parentheses

	ASD (*n =* 30)	TD (*n =* 29)	Ratio of ASD/TD	t-test	FDR
Fatigue	1.15 (1.0)	0.79 (0.8)	1.46	n.s.
Fibromyalgia	0.11 (0.6)	0 (0)		n.s.
Depression	0.67 (0.8)	0.48 (0.7)	1.38	n.s.
Irritability	0.78 (0.9)	0.71 (0.8)	1.09	n.s.
Anxiety	1.11 (0.9)	0.75 (1.0)	1.48	0.08	n.s.
Cognition	0.56 (1.0)	0.32 (0.6)	1.73	n.s.
Attention	0.85 (1.0)	0.32 (0.55)	2.65	0.056	n.s.
Sensory Sensitivity	0.44 (0.7)	0.18 (0.4)	2.49	n.s.
Stool/GI Problems	0.44 (0.8)	0.71 (1.0)	0.62	n.s.
Sleep Problems	0.74 (0.9)	0.46 (0.74)	1.60	n.s.
Headaches	0.56 (0.8)	0.64 (0.7)	0.86	n.s.
Chemical Sensitivity	0.19 (0.5)	0.14 (0.5)	1.30	n.s.
Allergies	0.78 (1.0)	0.71 (0.7)	1.09	n.s.
Average	0.60 (0.5)	0.44 (0.4)	1.37	n.s.

Other symptoms not listed were also reported. For the ASD-M group, multiple sclerosis, very sensitive to alcohol, and frequent boils were reported. For the TD-M group, nausea/pain from ovarian cyst, chronic pain, sensitive to loud noises, and touch aversive were reported. The symptoms were considered significantly different between the two groups if the p-value was less than or equal to 0.05 and the FDR was less than or equal to 0.1. GI in this case stands for gastrointestinal. The ratio of ASD/TD values refers to the ratio of the means of the data for ASD cases and TD cases

ISSN: 1471-2431