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Table 1 Geotemporospatial Regression

From: Contemporary epidemiology of rising atrial septal defect trends across USA 1991–2016: a combined ecological geospatiotemporal and causal inferential study

Instrumental ± Lagged Variables

Parameters & Values

Model

Parameter

β-Coefficient (95%C.I.)

P-value

LogLik

Parameters

Value

P-Value

 

Drugs

      
 

0 Lags

      
 

spreml(ASD_Rate ~ cigmon * mrjmon * abodalc + anlyr + cocyr)

Δ9THC_Exposure

mrjmon

0.49 (0.16, 0.82)

0.0033

−56.071

phi

2.57E-05

1

Cannabigerol_Exposure

cocyr

−0.25 (− 0.43, − 0.07)

0.0085

 

psi

0.9629

<2e-16

 

cigmon: mrjmon

−0.87 (−1.71, − 0.03)

0.0416

 

rho

− 0.0414

0.7944

     

lambda

−0.0455

0.7702

 

Drugs & 4 Races

      
 

0 Lags

      

Δ9THC_Exposure

spreml(ASD_Rate ~ cigmon * mrjmon * abodalc + anlyr + cocyr + 4_Races)

Cannabigerol_Exposure

mrjmon

0.49 (0.16, 0.82)

0.0033

−56.071

phi

2.57E-05

1

Caucasian_Daily_Score

cocyr

−0.25 (−0.43, − 0.07)

0.0085

 

psi

0.9629

<2e-16

African.Am_Daily_Score

cigmon: mrjmon

−0.87 (−1.71, − 0.03)

0.0416

 

rho

− 0.0414

0.7944

Asian.Am_Daily_Score

    

lambda

−0.0455

0.7702

AIAN_Daily_Score

       
 

Drugs

      
 

2 Lags

      
 

spreml(ASD_Rate ~ cigmon * mrjmon * abodalc + anlyr + cocyr)

Δ9THC_Exposure, 0:2

mrjmon

0.46 (0.07, 0.85)

0.0237

− 73.445

phi

15.4679

7.26E-07

Cannabigerol_Exposure, 0:2

    

psi

0.6471

0.0002

     

rho

−0.0352

0.8684

     

lambda

−0.0667

0.7517

 

Drugs

      
 

4 Lags

      
 

spreml(ASD_Rate ~ cigmon * mrjmon * abodalc + anlyr + cocyr)

Δ9THC_Exposure, 0:4

mrjmon: abodalc

19.44 (9.11, 29.77)

0.0002

−55.133

phi

1.3947

NA

Cannabigerol_Exposure, 0:4

cigmon: mrjmon: abodalc

−45.14 (− 75.09, − 15.19)

0.0031

 

psi

0.9530

<2e-16

     

rho

0.0204

0.9361

     

lambda

−0.1420

0.5256

  1. Abbreviations
  2. 4_Races Caucasian-American, African-American, Hispanic-American, Asian-American
  3. AIAN American Indian / Alaska Native
  4. Technical Notes:
  5. phi Idiosyncratic component of the spatial error term
  6. psi Individual time-invariant component of the spatial error term
  7. rho Spatial autoregressive parameter
  8. lambda Spatial autocorrelation coefficient