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Table 2 The detailed types and statistical significance between different congenital heart diseases in the study population (Group A versus Group B, acyanotic versus cyanotic subtypes)

From: Value of Galectin-3 assay in children with heart failure secondary to congenital heart diseases: a prospective study

Echo Findings

Group A (=45 children)

No. (%)

Group B (=30 children)

No. (%)

Test of significance

p value

Congenital acyanotic heart diseases

ASD

6 (13.3 %)

4 (13.3 %)

χ2(0.000)

1.0000

VSD

14 (31.1 %)

10 (33.4 %)

χ2(0.04085)

0.8398

PDA

7 (15.6 %)

5 (16.7 %)

χ2(0.01653)

0.8977

ASD+VSD

4 (8.9 %)

4 (13.3 %)

χ2(0.05247)

0.8188

PS

8 (17.8 %)

5 (16.7 %)

χ2(0.01551)

0.9009

Congenital MR

1 (2.2 %)

0 (0 %)

χ2(0.6757)

0.4111

Galectin-3 (ng/dl) in acyanotic heart diseases

 Mean ± SD

20.1±4.9

5.8±4.9

T (12.382)

< 0.0001*

Congenital cyanotic heart diseases

TGA

2 (4.4 %)

1 (3.3 %)

χ2(0.05787)

0.8099

TOF

3 (6.7 %)

1 (3.3 %)

χ2(0.01100)

0.9165

Galectin-3 (ng/dl) in cyanotic heart diseases

 Mean ± SD

19.9±5.1

6.2±4.3

T (12.114)

< 0.0001*

p value

P1= 0.8500

P2= 0.7380

-

-

  1. *Statistical significance
  2. χ2= Chi-squared test with Yate’s continuity correction, T= student t-test
  3. P1=comparison of serum galectin-3 between acyanotic and cyanotic heart disease (in Group A)
  4. P2=comparison of serum galectin-3 between acyanotic and cyanotic heart disease (in Group B)
  5. ASD atrial septal defect, VSD ventricular septal defect, PDA patent ductus arteriosus, PS pulmonary stenosis, MR mitral regurgitation, TGA transposition of great arteries, TOF tetralogy of fallot