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Table 1 Demographic, clinical, echocardiographic findings, and laboratory investigations of the studied groups

From: Value of Galectin-3 assay in children with heart failure secondary to congenital heart diseases: a prospective study

Data

Group A (No.=45)

Group B

(No =30)

Group C

(No=40)

Test of significance

P value

Clinico-demographic data

Sex

 Male no. (%)

24 (53.3)

17 (56.7)

20 (50)

χ2(0.03)

0.95

 Female no. (%)

21 (46.7)

13 (43.3)

20 (50)

Age(years)

 Mean ± SD

3.7 ± 2.89

3.9 ± 2.01

5.1 ± 3.95

K (0.88)

0.76

 Range

0.6-9.3

0.8-9.6

0.5– 10.3

  

Weight (Kg)

 Mean ± SD

8.35±3.9

8.5±3.8

9.8±4.7

K (0.95)

0.32

Height (cm)

     

 Mean ± SD

65.23 ± 15.9

70.8 ±16.2

72.2±22.4

F (0.61)

0.031*

BMI (Kg/m2)

     

 Mean ± SD

13.1± 2.9

14.4±2.6

16.7±2.3

F (0.60)

0.032*

HR

     

 Mean ± SD

127.5±17.1

81.4±9.3

70.3±6.7

F (159.2)

≤0.001*

Post Hoc : P1=≤0.001, P2=≤0.001, P3=0.03

RR

 Mean ± SD

46.5±13.4

37.5±6.5

35±7.1

F (10.1)

≤0.001*

Post Hoc : P4≤0.001, P5=≤0.001, P6=0.36

Systolic blood pressure

 Mean ± SD

93 ± 12.1

93.3 ±9.8

87±5.4

F (2.9)

0.06

Echo Findings

Ejection fraction %

 Mean ± SD

36.9±3.9

61.1±5.2

NA

T (36.8)

≤0.001*

 Range

32.8 – 40.8

55.7 – 66.9

Fractional Shortening %

 Mean ± SD

23.3±4.1

42.4±3.2

NA

T (20.1)

≤0.001*

 Range

18.8 – 28.5

37.6 – 45.1

LVEDD

 Mean ± SD

32.6± 11.1

29.1±3.1

NA

T (1.68)

0.0971

LVESD

 Mean ± SD

23.7± 6.7

13.7±2.3

NA

T (7.85)

≤0.001*

laboratory investigations

Hb (gm/dl)

 Mean ± SD

10.1±1.4

9.9±1.4

10.1±1.3

F ( 0.39)

0.67

Leucocyte count /cm3

 Mean ± SD

13.3± 3.9

13.7±3.7

7.4±3.7

K (24.4)

≤0.001*

Platelet/cm3

 Mean ± SD

240.6±62.2

236.7±61.2

236.4±59.2

F (0.04)

0.96

Serum creatinine

     

 Mean ± SD

0.59± 0.25

0.54±0.22

0.48±0.12

K (0.42)

0.0516

Galectin-3 (ng/dl)

 Mean ± SD

20.3±5.3

6.3±4.4

3.08±1.5

K (50.7)

≤0.001*

Post Hoc: P7=≤0.001, P8=≤0.001, P9=0.01

  1. *Statistical significance
  2. P1=comparison of HR between Group A and Group B, P2=comparison of HR between Group A and Group C
  3. P3=comparison of HR between Group B and Group C
  4. P4=comparison of RR between Group A and Group B, P5=comparison of RR between Group A and Group C
  5. P6=comparison of RR between Group B and Group C
  6. P7=comparison of serum galectin-3 between Group A and Group B, P8=comparison of serum galectin-3 between Group A and Group C, P9=comparison of serum galectin-3 between Group B and Control group