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Table 3 Mediation role of lean soft tissue on the association between training volume and BMD (n = 299).

From: Influential role of lean soft tissue in the association between training volume and bone mineral density among male adolescent practitioners of impact-loading sports: ABCD Growth study

Mediator aBMD (g/cm²) Total effect p-value Direct effect p-value Indirect effect p-value %Mediated
Boys (n = 299) Upper limbs 0.00243 0.009 0.00101 0.286 0.00142 0.002 58.37% 0.64
Lower limbs 0.00753 < 0.001 0.00562 < 0.001 0.00191 0.001 25.32% 0.78
Spine 0.00445 0.001 0.00296 0.007 0.00149 0.002 33.55% 0.67
Whole body 0.00465 < 0.001 0.00307 < 0.001 0.00158 0.001 33.96% 0.75
  1. Note: model adjusted for age, fat mass, age at peak of height velocity, and modality; LST lean soft tissue; aBMD areal bone mineral density. % mediation was only estimated for a significant indirect effect with a significant total effect.