Table 2 Neonatal outcomes of various doses of human milk intake in first 4 weeks of life
From: Dose-dependent effect of human milk on Bronchopulmonary dysplasia in very low birth weight infants
Neonatal outcomes | Daily volume of human milk, ml/kg body weight | ||||||
|---|---|---|---|---|---|---|---|
0 | 1–24 | 25–49 | ≥50 | sum | Statistical value | P-value | |
Main outcomes, n (%) | |||||||
 BPD | 112 (40.1) | 52 (40.6) | 48 (34.5) | 115 (27.5) | 327 (33.9) | χ2 = 15.069 | 0.002 |
 Moderate-severe BPD | 45 (16.1) | 15 (11.7) | 13 (9.4) | 37 (8.9) | 110 (11.4) | χ2 = 9.447 | 0.024 |
Secondary outcomes, n (%) | |||||||
 NEC | 30 (10.8) | 18 (14.1) | 22 (15.8) | 16 (3.8) | 86 (8.9) | χ2 = 26.821 | 0.000 |
 NEC (≥Bell’s stage 2) | 3 (1.1) | 3 (2.3) | 3 (2.2) | 5 (1.2) | 14 (1.5) | χ2 = 1.664 | 0.645 |
 Late-onset sepsis | 55 (19.7) | 34 (26.6) | 27 (19.4) | 39 (9.3) | 155 (16.1) | χ2 = 28.419 | 0.000 |
 EUGR | 160 (57.6) | 69 (54.3) | 60 (43.8) | 155 (38.5) | 444 (47.0) | χ2 = 27.531 | 0.000 |