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Table 3 Diagnostic test accuracy of C-reactive protein for diagnosing serious infection

From: Diagnostic test accuracy of point-of-care procalcitonin to diagnose serious bacterial infections in children

CRP mg/l Sensitivity (95% CI) Specificity (95% CI) Negative Predictive Value (95% CI) Positive Predictive Value (95% CI) Negative Likelihood Ratio (95% CI) Positive Likelihood Ratio
(95% CI)
10 0.90(0.54 to 0.99) 0.40(0.33 to 0.48) 0.99(0.92 to 1.00) 0.07(0.04 to 0.14) 0.25(0.04 to 1.61) 1.51(1.19 to 1.91)
20 0.70(0.35 to 0.92) 0.52(0.45 to 0.59) 0.97(0.91 to 0.99) 0.07(0.04 to 0.14) 0.58(0.22 to 1.51) 1.45(0.94 to 2.24)
30 0.60(0.27 to 0.86) 0.63(0.55 to 0.69) 0.97(0.92 to 0.99) 0.08(0.03 to 0.17) 0.64(0.30 to 1.37) 1.61(0.94 to 2.75)
50 0.50(0.20 to 0.80) 0.78(0.72 to 0.84) 0.97(0.92 to 0.99) 0.11(0.04 to 0.24) 0.64(0.34 to 1.19) 2.30(1.17 to 4.51)
75 0.40(0.14 to 0.73) 0.87(0.81 to 0.91) 0.97(0.92 to 0.99) 0.13(0.04 to 0.32) 0.69(0.42 to 1.15) 2.97(1.28 to 6.87)
100 0.40(0.14 to 0.73) 0.93(0.89 to 0.96) 0.97(0.92 to 0.99) 0.24(0.08 to 0.50) 0.64(0.39 to 1.07) 5.94(2.36 to 14.95)
150 0.20(0.04 to 0.56) 0.97(0.94 to 0.99) 0.96(0.92 to 0.98) 0.29(0.05 to 0.70) 0.82(0.60 to 1.12) 7.72(1.70 to 35.00)
200 0.10(0.01 to 0.46) 0.99(0.96 to 1.00) 0.96(0.91 to 0.98) 0.33(0.02 to 0.87) 0.91(0.74 to 1.12) 9.65(0.95 to 97.7)
  1. CI Confidence Interval